Influenza-induced rhabdomyolysis

Runnstrom, Martin; Ebied, Alex M.; Khoury, Adonice; Reddy, Raju

doi:10.1136/bcr-2018-226610

Cited by 24 publications

(23 citation statements)

References 28 publications

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“…Although VV ECMO initially rescued the patient, influenza-related biventricular dysfunction and fatal rhabdomyolysis with CK elevation > 200,000 contributed to the patient's decompensation. Influenza associated rhabdomyolysis has been previously reported in case reports in literature [22][23][24][25][26][27][28][29][30][31]. Recent review of literature in 2015 revealed twelve case reports with CK levels ranging from 1317 to 1,127,000 with mean value of 206, 908, with survival of 83% [18].…”

Section: Discussionmentioning

confidence: 99%

“…Recent review of literature in 2015 revealed twelve case reports with CK levels ranging from 1317 to 1,127,000 with mean value of 206, 908, with survival of 83% [18]. An additional six cases have been reported in the literature since then [25][26][27][28][29][30][31]. It is quite plausible that influenza related rhabdomyolysis is much more common and only the severely ill are being reported in the literature.…”

Section: Discussionmentioning

confidence: 99%

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Deadly combination of Vaping-lnduced lung injury and Influenza: case report

Akkanti¹,

Hussain²,

Patel³

et al. 2020

Diagn Pathol

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Background: E-cigarette and vaping use-associated acute lung injury (EVALI) has been recently recognized as a complication in individuals who use vaping devices. Another consideration is that EVALI may have an adverse influence on the outcome of intercurrent respiratory infections. We document this deadly combination in the case of a young man who had EVALI and simultaneous Influenza-A infection leading to severe Acute Respiratory Distress Syndrome (ARDS). Case presentation: A 27-year-old male with a history of tobacco and vaping use was admitted to hospital after two weeks of flu-like symptoms, diarrhea and vomiting. A chest x-ray was consistent with multifocal pneumonia, and microbiological tests were positive for Influenza-A and methicillin-sensitive Staphalacoccus aureus (MSSA). Bronchoscopy provided evidence of acute inhalational injury. After admission, he acutely decompensated with severe hypoxia and hypotension; he required intubation, sedation and vasopressors. He developed sepsis with acute kidney failure, liver failure, biventricular systolic dysfunction and severe rhabdomyolysis. He was placed on veno-venous (VV) extracorporeal membrane oxygenation (ECMO) initially and later changed to Veno-Arterial (VA) ECMO. Nevertheless, the patient continued to deteriorate, and he expired two weeks after admission. Conclusion: This case documents that EVALI can act as a major factor leading a respiratory infection to progress into severe ARDS with a fatal outcome.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Deadly combination of Vaping-lnduced lung injury and Influenza: case report

Akkanti¹,

Hussain²,

Patel³

et al. 2020

Diagn Pathol

View full text Add to dashboard Cite

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“…3 4 Rhabdomyolysis has been associated with viral infections and especially influenza. 5 It has also been reported in association with SARS. 6 Our patient presented with clinical and biochemical evidence of rhabdomyolysis before he was started on any drug or had been placed on paralytic therapy for mechanical ventilation, which are known causes of muscular injury.…”

Section: Discussionmentioning

confidence: 91%

Rhabdomyolysis as an initial presentation in a patient diagnosed with COVID-19

et al. 2020

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The presence of rhabdomyolysis secondary to multiple infections has been reported, predominantly viral, but also bacterial and fungal. It is well known that COVID-19 can present a wide variety of complications during the course of infection; however, the presence of rhabdomyolysis as an initial condition has not been reported so far. We report a case of rhabdomyolysis as an initial presentation in a patient diagnosed with SARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus 2) infection.

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“…In an adult study of 505 patients, high CK levels at admission were found to be associated with renal failure, dialysis requirement, mechanical ventilation, and prolonged hospital stay. 13 There are 42 cases of virus-induced rhabdomyolysis documented in the literature; influenza accounted for 14 of 42 (33%) of these reported cases. 9 In our case, viral infections, especially influenza, were investigated at the initial stage of diagnosis, and, then, COVID-19 was detected by the RT-PCR test.…”

Section: Discussionmentioning

confidence: 99%

Case Report: A COVID-19 Patient Presenting with Mild Rhabdomyolysis

Uysal

İkitimur

Yavuzer

et al. 2020

The American Journal of Tropical Medicine and Hygiene

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The news was reported from the Wuhan region of China about a novel corona virus in the end of 2019. After spreading around the world, a pandemic was declared by the WHO. Depending on the different involvement of the disease, the most common symptoms are fever, cough, and dyspnea. However, some indeterminate symptoms that make diagnosis difficult, such as myalgia and fatigue, can also be seen alone, without the typical clinical picture. We describe a patient with COVID-19 pneumonia, the only complaint of which is myalgia, and the first diagnosis is mild rhabdomyolysis. The patient had no evidence or history other than viral infection that could explain muscle pain and also increased level of muscle enzymes. When mild rhabdomyolysis lack of myoglobinuria and complications was diagnosed, treatment-related rhabdomyolysis was also avoided as no treatment related to COVID-19 was initiated yet. Apart from the typical symptoms leading to the typical diagnosis of COVID-19 at the first admission, SARS-CoV-2 related with rhabdomyolysis should also be kept in mind.

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Influenza-induced rhabdomyolysis

Cited by 24 publications

References 28 publications

Deadly combination of Vaping-lnduced lung injury and Influenza: case report

Deadly combination of Vaping-lnduced lung injury and Influenza: case report

Rhabdomyolysis as an initial presentation in a patient diagnosed with COVID-19

Case Report: A COVID-19 Patient Presenting with Mild Rhabdomyolysis

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