2018
DOI: 10.1080/21645515.2017.1423153
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Influenza vaccines: Evaluation of the safety profile

Abstract: The safety of vaccines is a critical factor in maintaining public trust in national vaccination programs. Vaccines are recommended for children, adults and elderly subjects and have to meet higher safety standards, since they are administered to healthy subjects, mainly healthy children. Although vaccines are strictly monitored before authorization, the possibility of adverse events and/or rare adverse events cannot be totally eliminated.Two main types of influenza vaccines are currently available: parenteral … Show more

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Cited by 61 publications
(33 citation statements)
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“…Vaccine safety profiles were similar in high-risk and healthy subjects, with predictably higher frequencies of mild-to-moderate AEs experienced after aIIV4 administration. 25 …”
Section: Discussionmentioning
confidence: 99%
“…Vaccine safety profiles were similar in high-risk and healthy subjects, with predictably higher frequencies of mild-to-moderate AEs experienced after aIIV4 administration. 25 …”
Section: Discussionmentioning
confidence: 99%
“…The term SAE indicates “ A serious adverse event (experience) or reaction is any untoward medical occurrence that at any dose results in death or is life-threatening” [ 88 ]. SAEs have to be compulsorily notified [ 89 ].…”
Section: A Novel Quadrivalent Inactivated Influenza Vaccine: Vaxigmentioning
confidence: 99%
“…The other major challenging factor for the development of a vaccine against RNA virus is its ultra-fast mutation rate and critical adverse effects associated with it. For instance, initial trails of the Flu vaccine in 2009 show mild adverse effects like tenderness in muscles, pain at the injection site, headache, malaise, and muscle pain (8). WHO recommended this vaccine for the different flulike syndrome as there are no significant differences in their adverse effects.…”
Section: Introductionmentioning
confidence: 99%