Infodemiology of Bell’s palsy: Tracing the seasonality of facial paralysis

Salbaş, Ender; Ketenci, Sertaç

doi:10.3233/bmr-210021

Cited by 3 publications

(2 citation statements)

References 18 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In Taiwan, the fluVc is only administered for a short period each year, especially from October to December, middle autumn to early winter . It may take bias when using SCCS if the incidence of BP varies with different seasons, which is a concern because previous studies have examined the association between seasonal variation and the onset of BP . Fortunately, the present findings indicated that seasonality did not affect BP incidence in this SCCS.…”

Section: Discussionmentioning

confidence: 61%

“…6,7,9 It may take bias when using SCCS if the incidence of BP varies with different seasons, which is a concern because previous studies have examined the association between seasonal variation and the onset of BP. 22,[44][45][46][47] Fortunately, the present findings indicated that seasonality did not affect BP incidence in this SCCS. The diagnosis of BP is made after various conditions that mimic BP have been excluded.…”

Section: Discussionmentioning

confidence: 73%

See 1 more Smart Citation

Association of Influenza Vaccination With Risk of Bell Palsy Among Older Adults in Taiwan

Wei

Wang

et al. 2023

JAMA Otolaryngol Head Neck Surg

View full text Add to dashboard Cite

ImportanceAnnual administration of the influenza vaccine (fluVc) is currently the most effective method of preventing the influenza virus in older adults. However, half of adults older than 65 years remain unvaccinated in Taiwan, possibly because of concern about adverse events, such as Bell palsy (BP). Currently, studies on the association between fluVc and risk of BP are inconsistent.ObjectiveTo determine whether the incidence of BP increases following fluVc in older adults.Design, Setting, and ParticipantsA self-controlled case series study design was used. Days 1 through 7, days 8 through 14, days 15 through 30, and days 31 through 60 following fluVc were identified as risk intervals, and days 61 through 180 were considered the control interval. A total of 4367 vaccinated individuals aged 65 years or older who developed BP within 6 months following fluVc were enrolled. Population-based retrospective claims data were obtained between 2010 and 2017; data were analyzed from April 2022 through September 2022.ExposureGovernment-funded seasonal fluVc.Main Outcomes and MeasuresThe outcome of interest was BP onset in risk intervals compared with control intervals. Three or more consecutive diagnoses of BP within 60 days following fluVc were used as the definition of a patient with BP. Poisson regression was used to analyze the incidence rate ratio (IRR) of risk intervals compared with control intervals.ResultsIn total, 13 261 521 patients who received the fluVc were extracted from the National Health Insurance Research Database in Taiwan from January 1, 2010, to December 31, 2017. Of those, 7 581 205 patients older than 65 years old met the inclusion criteria. The number of patients with BP diagnosed within 6 months following fluVc enrolled for risk analysis was 4367 (mean [SD] age, 74.19 [5.97] years; 2349 [53.79%] female patients). The incidence rate of BP among all observed fluVc older adults was 57.87 per 100 000 person-years. The IRRs for BP on days 1 through 7, days 8 through 14, and days 15 through 30 were 4.18 (95% CI, 3.82-4.59), 2.73 (95% CI, 2.45-3.05), and 1.67 (95% CI, 1.52-1.84), respectively. However, there was no increase during days 31 through 60 (IRR, 1.06; 95% CI, 0.97-1.16). The postvaccination risk of BP was consistent across all subgroups stratified by sex, age group, and baseline conditions.Conclusions and RelevanceThe present self-controlled case series indicated that the risk of BP in individuals older than 65 years increased within the first month, especially within the first week, following fluVc. But overall, the adverse event rate of BP was low, and considering the morbidity and mortality of influenza infection, the benefits of fluVc still outweigh the risks.

show abstract

Section: Discussionmentioning

confidence: 61%

Section: Discussionmentioning

confidence: 73%

Association of Influenza Vaccination With Risk of Bell Palsy Among Older Adults in Taiwan

Wei

Wang

et al. 2023

JAMA Otolaryngol Head Neck Surg

View full text Add to dashboard Cite

show abstract

Characterizing the Online Discourse on Facial Paralysis: What Patients Are Asking and Where They Find Answers

von Sneidern,

Saaedi,

Varelas

et al. 2024

Facial Plastic Surgery & Aesthetic Medicine

View full text Add to dashboard Cite

Non-Linear Association Between Climatic Parameters and Bell’s Palsy Prevalence of Hospital Outpatients: An Ecological Proof in Kunshan, Suzhou, China

Zhang,

Jiang,

et al. 2024

Dose-Response

View full text Add to dashboard Cite

Objective This study aimed to explore the relationship between climatic parameters and the daily cases of Bell’s palsy (BP) among hospital outpatients, providing ecological evidence for understanding BP etiology and prevention. Methods Retrospective analysis was conducted on data from 2187 BP patients who attended Kunshan First People’s Hospital Outpatient Clinic from January 1, 2020, to December 31, 2022. Meteorological data, including temperature, relative humidity, precipitation, wind speed, sunshine duration, and atmospheric pressure, were collected and combined with daily BP case records. Additionally, air quality index was used as a covariate. Results The number of new BP cases among outpatients showed a negative correlation with average daily temperature. A nonlinear relationship between daily average temperature and BP cases was observed through the generalized additive model (GAM). A significant negative correlation was identified between daily average temperature and BP cases, with inflection points at temperatures above 4.2°C, suggesting a potential decrease in BP risk with temperature rise beyond this threshold. Conclusion This study provides ecological evidence of a link between climatic factors and BP occurrence. Temperature demonstrated a significant nonlinear negative correlation with daily BP incidence, highlighting temperature and cold exposure as key targets for BP prevention in Kunshan.

show abstract

Infodemiology of Bell’s palsy: Tracing the seasonality of facial paralysis

Cited by 3 publications

References 18 publications

Association of Influenza Vaccination With Risk of Bell Palsy Among Older Adults in Taiwan

Association of Influenza Vaccination With Risk of Bell Palsy Among Older Adults in Taiwan

Characterizing the Online Discourse on Facial Paralysis: What Patients Are Asking and Where They Find Answers

Non-Linear Association Between Climatic Parameters and Bell’s Palsy Prevalence of Hospital Outpatients: An Ecological Proof in Kunshan, Suzhou, China

Contact Info

Product

Resources

About