Information Coding in a Reconfigurable DNA Origami Domino Array

Fan, Sisi; Wang, Dongfang; Cheng, Jin; Liu, Yan; Luo, Tao; Cui, Daxiang; Ke, Yonggang; Song, Jie

doi:10.1002/anie.202003823

Cited by 59 publications

(41 citation statements)

References 69 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Here, we propose to exploit the self‐assembly and reconfiguration abilities of DNA origami technique to introduce general mechanisms for self‐repair within defective or externally damaged nanostructures [9, 25–27] . We classify self‐repair mechanisms in two categories, that is, self‐regenerating and self‐healing systems as explained in the following.…”

Section: Introductionmentioning

confidence: 99%

Self‐Regeneration and Self‐Healing in DNA Origami Nanostructures

et al. 2021

View full text Add to dashboard Cite

DNA nanotechnology and advances in the DNA origami technique have enabled facile design and synthesis of complex and functional nanostructures. Molecular devices are, however, prone to rapid functional and structural degradation due to the high proportion of surface atoms at the nanoscale and due to complex working environments. Besides stabilizing mechanisms, approaches for the self‐repair of functional molecular devices are desirable. Here we exploit the self‐assembly and reconfigurability of DNA origami nanostructures to induce the self‐repair of defects of photoinduced and enzymatic damage. We provide examples of repair in DNA nanostructures showing the difference between unspecific self‐regeneration and damage specific self‐healing mechanisms. Using DNA origami nanorulers studied by atomic force and superresolution DNA PAINT microscopy, quantitative preservation of fluorescence properties is demonstrated with direct potential for improving nanoscale calibration samples.

show abstract

Section: Introductionmentioning

confidence: 99%

Self‐Regeneration and Self‐Healing in DNA Origami Nanostructures

et al. 2021

View full text Add to dashboard Cite

show abstract

“…Using this system, they also achieved steganography and cryptography synchronously on DNA nanostructures. [ 14 ]…”

Section: In Vitro Data Storage Based On Dna Nanoengineeringmentioning

confidence: 99%

“…Both sequence and structure information permit data cryptography. [ 12–14 ] Sequestering DNA in other materials allows hiding data in everyday objects, which is attractive for information steganography. [ 15 ]…”

Section: Introductionmentioning

confidence: 99%

Data Storage Based on DNA

Hao

Fan

et al. 2020

Small Structures

View full text Add to dashboard Cite

Recent years have witnessed the exponential growth of information, calling for the development of new storage media. DNA provides an attractive alternative for data storage due to its high physical density, reproducibility, and excellent durability that have been tested by nature. Rapid progress has been made during the past decade by exploiting artificially designed DNA materials for data storage. Herein, recent advances of DNA‐based encoding, writing, storage, retrieving, reading, and decoding for data storage are summarized. In addition to encoding with nucleic acid sequences, different forms of data storage strategies using DNA nanostructures are also highlighted. Also, in vivo DNA data storage, especially with the use of clustered regularly interspaced short palindromic repeat–Cas systems, is discussed. The challenges and opportunities for the development and application of DNA‐based data storage are presented.

show abstract

“…[24] Wirs chlagen vor,d ie selbst-assemblierenden und rekonfigurierbaren Eigenschaften der DNA-Origami-Technik auszunutzen, um allgemeine Selbstreparaturmechanismen in defekten oder extern beschädigten Nanostrukturen einzuführen. [9,[25][26][27] Wiru nterteilen solche Selbstreparaturmechanismen in zwei Kategorien, d. h. in selbstregenerierende und selbstheilende Systeme,w ie im Folgenden erläutert wird. Schema 1zeigt ein funktionelles molekulares Nanogerät, das durch ein Kraftübertragungssystem mit Zahnrädern dargestellt wird.…”

Section: Introductionunclassified

Selbstregeneration und Selbstheilung in DNA‐Origami‐Nanostrukturen

et al. 2021

View full text Add to dashboard Cite

DNA‐Nanotechnologie und Fortschritte in der DNA‐Origami‐Technik haben das einfache Design und die Synthese komplexer und funktioneller Nanostrukturen ermöglicht. Jedoch sind molekulare Geräte aufgrund des hohen Anteils von Oberflächenatomen und der komplexen Einsatzbedingungen im Nanomaßstab anfällig für eine schnelle funktionelle und strukturelle Degradierung. Neben Stabilisierungsmechanismen sind Ansätze zur Selbstreparatur funktioneller molekularer Geräte wünschenswert. Hier nutzen wir die selbst‐assemblierenden und rekonfigurierbaren Eigenschaften von DNA‐Origami‐Nanostrukturen für die Selbstreparatur von photoinduzierten und enzymatischen Schäden aus. Wir geben Beispiele für die Reparatur von DNA‐Nanostrukturen, die den Unterschied zwischen unspezifischer Selbstregeneration und schadensspezifischer Selbstheilung aufzeigen. Anhand von DNA‐Origami‐Nanolinealen, die mit Rasterkraftmikroskopie und DNA‐PAINT‐Superauflösungs‐Mikroskopie untersucht wurden, demonstrieren wir die quantitative Aufrechterhaltung der Fluoreszenzeigenschaften mit direktem Potenzial zur Verbesserung nanoskaliger Kalibrierproben.

show abstract

Information Coding in a Reconfigurable DNA Origami Domino Array

Cited by 59 publications

References 69 publications

Self‐Regeneration and Self‐Healing in DNA Origami Nanostructures

Self‐Regeneration and Self‐Healing in DNA Origami Nanostructures

Data Storage Based on DNA

Selbstregeneration und Selbstheilung in DNA‐Origami‐Nanostrukturen

Contact Info

Product

Resources

About