The information support systems of enterprises and the tasks they perform are considered. An analysis of the basic requirements for information support systems was carried out. The basic principles of system analysis applicable to the design of an information support system are considered. The main directions of interaction between the enterprise information support system and other systems are identified based on the principles of system analysis. The information support system interacts with other systems based on the principles of system analysis, using data and analytical tools to make decisions on enterprise management and monitor the operation of other systems. The direction of ensuring security for the information support system is separately considered. The main stages of designing an information support system are formulated based on the principles of system analysis. Recommendations have been put forward for the further development of the information support system based on the principles of system analysis. These recommendations will help the enterprise continue to develop and improve the information support system in accordance with its needs and strategic goals.