Information transport by sine-Gordon solitons in microtubules

Abdalla, Élcio; Maroufi, B.; Cuadros-Melgar, Bertha; Sedra, M. B.

doi:10.1016/s0378-4371(01)00399-5

Cited by 26 publications

(14 citation statements)

References 9 publications

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“…Since we do not have any practical means to either measure the spin variable s , or account for its dynamical details, we assume its quantum average as suggested by Abdalla et al (2001). Such an average is easily obtained due to the simple description of s in terms of the Pauli matrices, leading to a result expressed in terms of the exponential of the field θ , defined by:…”

Section: Coherent Photon Emission Pulse Modesmentioning

confidence: 99%

Solitonic Effects of the Local Electromagnetic Field on Neuronal Microtubules

Georgiev¹,

Papaioanou²,

Glazebrook³

2007

Neuroquantology

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Current wisdom in classical neuroscience suggests that the only direct action of the electric field in neurons is upon voltage-gated ion channels which open and close their gates during the passage of ions. The intraneuronal biochemical activities are thought to be modulated indirectly either by entering into the cytoplasmic ions that act as second messengers or via linkage to the ion channels enzymes. In this paper we present a novel possibility for the subneuronal processing of information by cytoskeletal microtubule tubulin tails and we show that the local electromagnetic field supports information that could be converted into specific protein tubulin tail conformational states. Long-range collective coherent behavior of the tubulin tails could be modelled in the form of solitary waves such as sine-Gordon kinks, antikinks or breathers that propagate along the microtubule outer surface, and the tubulin tail soliton collisions could serve as elementary computational gates that control cytoskeletal processes. The biological importance of the presented model is due to the unique biological enzymatic energize action of the tubulin tails, which is experimentally verified for controlling the sites of microtubule-associated protein attachment and the kinesin transport of post-Golgi vesicles.

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Section: Coherent Photon Emission Pulse Modesmentioning

confidence: 99%

Solitonic Effects of the Local Electromagnetic Field on Neuronal Microtubules

Georgiev¹,

Papaioanou²,

Glazebrook³

2007

Neuroquantology

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“…The standing breather swinging at certain tubulin tail (or breather formed by 2-3 coupled swinging tubulin tails) could catalyze microtubule attachment proteins (MAP) and promote or inhibit the action of kinesin-proteins involved in the microtubule dynamics. 82) Another interesting result of the work of Abdalla et al 81) is the fact that the frequency parameters, which showed up in the model, are compatible with the size of microtubules of brain structures and with the transition period observed for the so called conformational changes of the tubulin dimer protein (namely 1-100 GHz).…”

Section: The Word Soliton Emanates From John Scott Russell's Observatmentioning

confidence: 81%

“…Such interaction occurs with the dipole moments of the molecules in the brain microtubules. 79) Abdalla et al 81) studied the problem of information propagation in the brain microtubules, considering propagation of electromagnetic waves in a fluid of permanent electric dipoles. The problem reduces to sine-Gordon wave equation in one space and one time dimension.…”

Section: The Word Soliton Emanates From John Scott Russell's Observatmentioning

confidence: 99%

The Mammalian Brain in the Electromagnetic Fields Designed by Man with Special Reference to Blood-Brain Barrier Function, Neuronal Damage and Possible Physical Mechanisms

Salford

Nittby

Brun

et al. 2008

Prog. Theor. Phys. Suppl.

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Life on earth was formed during billions of years, exposed to, and shaped by the original physical forces such as gravitation, cosmic irradiation, atmospheric electric fields and the terrestrial magnetism. The Schumann resonances at 7.4 Hz are an example of oscillations possibly important for life. 1)The existing organisms are created to function in harmony with these forces. However, in the late 19th century mankind introduced the use of electricity, in the early 20th century long-wave radio and in the 1940-ies short-wave radio. High frequency RF was introduced in the 50-ies as FM and television and during the very last decades, microwaves of the modern communication society spread around the world. Today, however, one third of the world's population is owner of the microwave-producing mobile phones and an even larger number is exposed to the cordless RF emitting systems. To what extent are all living organisms affected by these, almost everywhere present radio frequency fields? And what will be the effects of many years of continuing exposure?Since 1988 our group has studied the effects upon the mammalian blood-brain barrier (BBB) in rats by non-thermal radio frequency electromagnetic fields (RF-EMF). These have been shown to cause significantly increased leakage of the rats' own blood albumin through the BBB of exposed rats, at energy levels of 1W/kg and below, as compared to non-exposed animals in a total series of about two thousand animals. 2)−6) One remarkable observation is the fact that the lowest energy levels, with whole-body average power densities below 10mW/kg, give rise to the most pronounced albumin leakage. If mobile communication, even at extremely low energy levels, causes the users' own albumin to leak out through the BBB, also other unwanted and toxic molecules in the blood, may leak into the brain tissue and concentrate in and damage the neurons and glial cells of the brain.In later studies we have shown that a 2-h exposure to GSM 915 MHz, at non-thermal SAR-values of 0.2, 2 and 200 mW/kg, gives rise to significant neuronal damage, seen not only 50 days after the exposure 7) but also after 28 days but not after 14 days. Albumin extravasations and uptake into neurons was enhanced after 14 days, but not after 28. 8) In our continued research, also the non-thermal effects on tissue structure and memory function of long-term exposure for 13 months are studied. 9) We have also performed microarray analysis of brains from rats exposed to short term GSM both at 1,800 MHz and at 900MHz and have found significant effects upon gene expression of membrane associated genes as compared to control animals. 10), 11) Most of our findings support that living organisms are affected by the non-thermal radio frequency fields. Some other studies agree while others find no effects.

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“…For the case of sine-Gordon solitons, the information transport has been investigated by Abdalla et al [21].…”

Section: Quantum Information In the Mt Wallsmentioning

confidence: 99%

Supersymmetric Methods in the Traveling Variable: Inside Neurons and at the Brain Scale

Rosu¹,

Cornejo-Pérez²,

Perez-Terrazas³

2008

Physics of Emergence and Organization

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We apply the mathematical technique of factorization of differential operators to two different problems. First we review our results related to the supersymmetry of the Montroll kinks moving onto the microtubule walls as well as mentioning the sine-Gordon model for the microtubule nonlinear excitations. Second, we find analytic expressions for a class of one-parameter solutions of a sort of diffusion equation of Bessel type that is obtained by supersymmetry from the homogeneous form of a simple damped wave equations derived in the works of P.A. Robinson and collaborators for the corticothalamic system. We also present a possible interpretation of the diffusion equation in the brain context.

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Information transport by sine-Gordon solitons in microtubules

Cited by 26 publications

References 9 publications

Solitonic Effects of the Local Electromagnetic Field on Neuronal Microtubules

Solitonic Effects of the Local Electromagnetic Field on Neuronal Microtubules

The Mammalian Brain in the Electromagnetic Fields Designed by Man with Special Reference to Blood-Brain Barrier Function, Neuronal Damage and Possible Physical Mechanisms

Supersymmetric Methods in the Traveling Variable: Inside Neurons and at the Brain Scale

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