Informativity Of Proteinograms As A Clinical-Diagnostic Test At Dispoteinemia In The Age Aspect

Yeriomenko, R. F.; Ostapets, M. O.

doi:10.5281/zenodo.399312

Cited by 2 publications

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“…and Ostapets R.O. [8] found that "the proteinogram has certain differences depending on age, so these aspects should be consid-ered when diagnosing certain pathological conditions in different age groups".…”

Section: огляди літератури / Literature Reviewsmentioning

confidence: 99%

“…[7] У своїх дослідженнях Єременко Р.Ф., Остапець Р.О. [8] встановили, що « протеїнограма має певні відмінності в залежності від віку, тому дані аспекти необхідно враховувати при діагностиці певних патологічних станів у різних вікових групах ».…”

Section: огляди літератури / Literature Reviewsunclassified

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Theoretical Prerequisites of the Value of Protein in Food Products and in the Daily Diet

Snisar,

Rudyshyna

2023

VPBM

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Proteins are vital macronutrients, without which the development of the body is impossible. Proteins are involved in the development and differentiation of cells and the structure of organs and systems. Depending on the diet, the amount of proteins in the blood plasma can vary, leading to protein and protein-energy deficiencies. Accordingly, determining the impact of protein deficiency on human health, particularly on the occurrence of diseases associated with changes in cancer pressure and renal dysfunction, led to the formulation of the study aim.This review article aimed to systematise scattered knowledge, collect information on the state of the research on the issue, review the literature, compare data from different sources, review new knowledge with trends in developing this knowledge, identify new research areas, and review promising ideas. The review literature identifies several essential functions performed by proteins in the body.It has been found that a deficiency of protein in the diet leads to an imbalance in protein metabolism and changes in the volume of intravascular space.The descriptive review helped to identify the causes and treatment of hypoproteinaemia and dysproteinemia. Deficiency of proteins in the blood directly impacts the kidneys, causing damage to their tissues. Proteins are divided into simple and complex. Simple proteins include albumin, globulins, histones, protamines, and scleroproteins. Complex proteins include nucleoproteins, lipoproteins, glycoproteins, chromoproteins, and metalloproteins. Various biochemical blood parameters are used to diagnose kidney disease, including total protein, albumin, globulins, and others. Changes in these parameters may indicate the presence of pathological conditions associated with renal dysfunction.If the deficiency is extremely severe, various approaches are used to treat kidney-related impairment, including protein fortification, protein supplements, or infusions. It can help restore the balance of proteins in the blood and improve kidney function. Maintaining oncotic pressure with protein foods in the diet is very important to prevent kidney disease. It is concluded that starvation or insufficient protein intake contributes to the occurrence of diseases that negatively affect the standard of living.

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Section: огляди літератури / Literature Reviewsmentioning

confidence: 99%

Section: огляди літератури / Literature Reviewsunclassified

Theoretical Prerequisites of the Value of Protein in Food Products and in the Daily Diet

Snisar,

Rudyshyna

2023

VPBM

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Non-specific factors of children protection with streptococcal tonsillitis and infected with herpes virus type 6

Olkhovska

Yeloyeva

Olkhovskyi

2021

SR:MS

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The aim of the work was to study the characteristics of the response of non-specific protective factors in tonsillitis of streptococcal etiology in children infected and uninfected with HHV-6 infection at different periods of the disease. Materials and research methods. In 78 children aged 3–15 years, inflammation markers and phagocytic activity of peripheral blood neutrophils (PAN) were determined using the nitroblue tetrazolium reduction test. The studies were carried out in the acute period and in the period of convalescence. Mathematical and statistical processing of the data obtained was carried out using Microsoft Excel 2003 and Statistica 6.0 programs. The significance of differences between the mean values was determined using the Student's test (t). Results. It was found that infection of children with HHV-6 leads to a decrease in the functional activity of neutrophils in the onset of streptococcal tonsillitis compared with uninfected patients (p<0.05). Also, the acute period of streptococcal tonsillitis in patients with co-infection is accompanied by a violation of the functional reserve of the oxygen-dependent mechanism of bactericidal neutrophils: minimal opportunities were found in tonsillitis on the background of HHV-6 infection (p<0.05). By the period of convalescence, a decrease in the indicators of the functional activity of neutrophils, increased in the acute period, was recorded, but in children infected with HHV-6, a complete recovery of indicators to the physiological norm did not occur. One of the features of streptococcal tonsillitis in children with HHV-6 infection is an increase in serum gamma globulin level (p˂0.05), lack of significant dynamics of decrease in the ASL-O indicator. Conclusions. The presence of VHL-6t infection in a child with streptococcal tonsillitis adversely affects the state of nonspecific protective factors, in particular PAN. The obtained data must be used to optimize the management of patients at different periods of the disease, including at the stages of dispensary observation

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Informativity Of Proteinograms As A Clinical-Diagnostic Test At Dispoteinemia In The Age Aspect

Cited by 2 publications

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Theoretical Prerequisites of the Value of Protein in Food Products and in the Daily Diet

Theoretical Prerequisites of the Value of Protein in Food Products and in the Daily Diet

Non-specific factors of children protection with streptococcal tonsillitis and infected with herpes virus type 6

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