Ingesta de una fórmula láctea suplementada con hierro como medida preventiva del déficit de hierro en niños de 1 a 3 años de edad

Lozano, J. Maldonado; Baró, L; Ramírez-Tortosa, MC; Gil, Fernanda García; Linde, Juan Máximo Molina; López‐Huertas, Eduardo; Boza, JJ; Gil, Artur

doi:10.1157/13107394

Cited by 19 publications

(4 citation statements)

References 17 publications

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“…These results are coherent since it is well known that dairy products are not the main dietetic sources of Zn and Fe (Freake & Sankavaram, 2013;Lönnerdal & Hernell, 2013). Moreover, in the last few years different formulations have been suggested to fortify with Fe these kinds of infant formulae (Maldonado Lozano et al, 2007). However, the same strategy should be also applied with Zn.…”

Section: Resultsmentioning

confidence: 56%

Probabilistic assessment of the intake of mineral and trace elements by consumption of infant formulas and processed cereal-based food in Spain

Moreno-Rojas

Cañal-Ruiz

Amaro-López

et al. 2014

CyTA - Journal of Food

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In this study a probabilistic model was developed to estimate the intake level of Fe, Zn, Ca, P, Mg, Mn, Cu, Na, and K derived from consumption of infant formulas and processed cereal-based food in Spain. Infant formulas were classified in two categories (first term and follow-on) while cereal-based foods were split up in six groups according to their composition (without gluten, only with gluten, fruits, honey, cocoa, and integral cereal). Contributions to Dietary Reference Intakes (DRIs) were studied for two population groups: 0-6-monthold and 6-month-1-year-old infants. The results reported that mineral and trace elements contents in these types of food cover the established DRIs for Ca, Mg, P, Fe, and K being relatively low for Zn and Cu. Conversely, Na and Mn contents were moderately high and should be decreased to reduce the prevalence of certain diseases.Se ha desarrollado un modelo probabilístico para determinar la ingesta de Fe, Zn, Ca, P, Mg, Mn, Cu, Na, y K a partir del consumo de fórmulas y cereales infantiles. Las fórmulas infantiles se clasificaron en dos categorías (inicio y continuación) y los cereales en seis categorías (con o sin gluten, con frutas, miel, cacao e integrales). Las contribuciones a la Ingestas Dietéticas de Referencia (IDR) se han realizado para dos grupos de población: bebés de 0-6 meses y de 6 meses-1 año. Los resultados muestran como el contenido de minerales y elementos traza presentes en este tipo de alimentos cubren la IDR establecida para Ca, Mg, P, Fe, K, y fueron bajos para cubrir la IDR de Zn y Cu. Por contra, el contenido de Na y Mn es alto y debe reducirse para reducir la incidencia de determinadas patologías.

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Section: Resultsmentioning

confidence: 56%

Probabilistic assessment of the intake of mineral and trace elements by consumption of infant formulas and processed cereal-based food in Spain

Moreno-Rojas

Cañal-Ruiz

Amaro-López

et al. 2014

CyTA - Journal of Food

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“…However, a sensitivity analysis including only studies with low risk of bias led to similar results (three studies that fulfilled 4 of 5 quality criteria [8,25,26]: hemoglobin increase 0.87 g/dl (95%-CI: 0.09 to 1.65; I 2 = 92%). Another sensitivity analysis showed that the result pattern remained basically unchanged after performing analyses using mean values of groups at the end of the study, instead of mean changes of groups.…”

Section: Resultsmentioning

confidence: 67%

“…Only two [8,25] of 18 trials provided enough information to conclude that both random sequence generation and allocation concealment was adequately performed (Table 3). For 11 trials this was unclear and inadequate procedures had been applied in 5 trials.…”

Section: Resultsmentioning

confidence: 99%

Effects of micronutrient fortified milk and cereal food for infants and children: a systematic review

et al. 2012

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BackgroundMicronutrient deficiency is a common public health problem in developing countries, especially for infants and children in the first two years of life. As this is an important time window for child development, micronutrient fortified complementary feeding after 6 months of age, for example with milk or cereals products, in combination with continued breastfeeding, is recommended. The overall effect of this approach is unclear.MethodsWe performed a Systematic Review and Meta-analysis to assess the impact of micronutrient fortified milk and cereal food on the health of infants and little children (aged 6 months to 5 years) compared to non-fortified food. We reviewed randomized controlled trials using electronic databases (MEDLINE and Cochrane library searches through FEB 2011), reference list screening and hand searches. Three reviewers assessed 1153 studies for eligibility and extracted data. One reviewer assessed risk of bias using predefined forms.ResultsWe included 18 trials in our analysis (n = 5’468 children; range of mean hemoglobin values: 9.0 to 12.6 g/dl). Iron plus multi micronutrient fortification is more effective than single iron fortification for hematologic outcomes. Compared to non-fortified food, iron multi micronutrient fortification increases hemoglobin levels by 0.87 g/dl (95%-CI: 0.57 to 1.16; 8 studies) and reduces risk of anemia by 57% (relative risk 0.43; 95%-CI 0.26 to 0.71; absolute risk reduction 22%; number needed to treat 5 [95%-CI: 4 to 6]; 6 Studies). Compared to non-fortified food, fortification increases serum levels of vitamin A but not of zinc. Information about functional health outcomes (e.g. weight gain) and morbidity was scarce and evidence is inconclusive. Risk of bias is unclear due to underreporting, but high quality studies lead to similar results in a sensitivity analysis.ConclusionsMulti micronutrient fortified milk and cereal products can be an effective option to reduce anemia of children up to three years of age in developing countries. On the basis of our data the evidence for functional health outcomes is still inconclusive.

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“…The so‐called growing‐up milks have a lower protein content than cow's milk and are supplemented with trace elements, including iron, vitamins, and essential fatty acids. Although the commercialisation of growing‐up milks continues to increase in many countries worldwide, particularly in Europe (16,17), their benefits are still a matter of debate. This controversy arose because the possible nutritional risks associated with the use of cow's milk and the expected benefits from the use of growing‐up milks have not been clearly demonstrated after the age of 1 year.…”

Section: Iron‐deficiency Anaemiamentioning

confidence: 99%

Is Cow's Milk Harmful to a Child's Health?

Agostoni

Turck

2011

J. pediatr. gastroenterol. nutr.

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Discussions and debates have recently emerged on the potential positive and negative effects of cow's milk in the paediatric community, also under the pressure of public opinion. The negative effects of cow's-milk consumption seem to be limited to iron status up to 9 to 12 months; then no negative effects are observed, provided that cow's milk, up to a maximum daily intake of 500 mL, is adequately complemented with iron-enriched foods. Lactose intolerance can be easily managed and up to 250 mL/day of milk can be consumed. Allergy to cow's-milk proteins is usually transient. Atopic children may independently be at risk for poor growth, and the contribution of dairy nutrients to their diet should be considered. The connection of cow's milk to autistic spectrum disorders is lacking, and even a cause-effect relation with type 1 diabetes mellitus has not been established because many factors may concur. Although it is true that cow's milk stimulates insulin-like growth factor-1 and may affect linear growth, association with chronic degenerative, noncommunicable diseases has not been established. Finally, fat-reduced milk, if needed, should be considered after 24 to 36 months. Cow's milk represents a major source of high nutritional quality protein as well as of calcium. Moreover, it has growth-promoting effects independent of specific compounds. Its protein and fat composition, together with the micronutrient content, is suggestive of a functional food, whose positive effects are emphasised by regular consumption, particularly under conditions of diets poor in some limiting nutrients, although in industrialised countries cow's milk's optimal daily intake should be around 500 mL, adequately complemented with other relevant nutrients.

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Ingesta de una fórmula láctea suplementada con hierro como medida preventiva del déficit de hierro en niños de 1 a 3 años de edad

Cited by 19 publications

References 17 publications

Probabilistic assessment of the intake of mineral and trace elements by consumption of infant formulas and processed cereal-based food in Spain

Probabilistic assessment of the intake of mineral and trace elements by consumption of infant formulas and processed cereal-based food in Spain

Effects of micronutrient fortified milk and cereal food for infants and children: a systematic review

Is Cow's Milk Harmful to a Child's Health?

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