Inguinal lymphadenopathy secondary to adenocarcinoma of caecum: A case report

Hakeem, Abdul; Khan, Mansoor A.; Dugar, Neelam; Muzaffar, Mahariz; Robinson, Joy

doi:10.2478/s11536-008-0094-y

Cited by 10 publications

(13 citation statements)

References 11 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Previous reports have claimed that possible mechanism of metastasizing from colon cancer to inguinal lymph nodes is that tumor invading to the abdominal wall metastasize to the inguinal lymph nodes through superficial lymphatic pathways along the inferior epigastric artery. Different from previous reports [3–7], our case was not confirmed tumor invasion to the abdominal wall but may have synchronous abdominal wall metastasis. It can be presumed that inguinal lymph node metastasis seems to originate from the abdominal wall metastasis, which seems to be the first case to date.…”

Section: Discussioncontrasting

confidence: 99%

“…Different from previous reports [3–7], our case was not confirmed tumor invasion to the abdominal wall but may have synchronous abdominal wall metastasis. It can be presumed that inguinal lymph node metastasis seems to originate from the abdominal wall metastasis, which seems to be the first case to date.…”

Section: Discussioncontrasting

confidence: 99%

“…A literature search of reports published in English identified only five cases of colon adenocarcinoma with inguinal lymph node metastasis [3–7]. In four of these cases, the primary tumor was suspected to invading the abdominal wall or skin, and was then thought to have metastasized to inguinal lymph nodes through the superficial lymphatic pathway along the inferior epigastric artery [3–5, 7]. In the remaining case, ascending colon cancer metastasized to external iliac and inguinal lymph nodes, suggesting that inguinal lymph node metastasis had occurred through the external iliac system [6].…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Metachronous metastasis to inguinal lymph nodes from sigmoid colon adenocarcinoma with abdominal wall metastasis: a case report

et al. 2019

View full text Add to dashboard Cite

Background Inguinal lymph node metastasis from rectum is uncommon but well-known occurrence, whereas that from colon adenocarcinoma is extremely rare. Inguinal lymph node metastasis from colon adenocarcinoma has only been reported in previous cases involving primary tumor invasion of the abdominal wall, or in those involving colon cancer metastasis to external iliac lymph nodes. We describe a case of inguinal lymph node metastasis from colon cancer without primary tumor invasion to the abdominal wall. Case presentation A 42-year-old female, who had undergone twice cesarean sections before, underwent open sigmoidectomy for sigmoid colon adenocarcinoma and received 12 cycles of FOLFOX regimen as adjuvant chemotherapy. Two years after sigmoidectomy, a follow-up CT scan revealed enlarged inguinal lymph nodes as well as growth of enhanced mass lesions on the abdominal wall at site of the cesarean section scar. Biopsy of both lesions revealed well-differentiated adenocarcinoma, and immunohistochemistry demonstrated positive expression of CDX2, substantiating its gastrointestinal origin. We therefore performed dissection of left inguinal lymph nodes and mass lesion of the abdominal wall. The patient died 51 months after lymph node dissection. Conclusions This is the first reported case of inguinal lymph node metastasis from colon cancer without invasion of the primary tumor to the abdominal wall or without involvement of the external iliac lymph nodes, suggesting that the pathway of inguinal metastasis originated from the abdominal wall metastasis. When inguinal lymph node metastasis from colon cancer is suspected, if an R0 resection was possible, inguinal lymph node dissection may be a potentially effective treatment. Electronic supplementary material The online version of this article (10.1186/s12885-019-5386-x) contains supplementary material, which is available to authorized users.

show abstract

Section: Discussioncontrasting

confidence: 99%

Section: Discussioncontrasting

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Metachronous metastasis to inguinal lymph nodes from sigmoid colon adenocarcinoma with abdominal wall metastasis: a case report

et al. 2019

View full text Add to dashboard Cite

show abstract

“…Metastasis from both right and sigmoid colon has been noticed [ 2 - 5 ]. A case reported by Hakeem et al noted the cecal carcinoma spreading to contralateral inguinal nodes [ 11 ].…”

Section: Discussionmentioning

confidence: 99%

Synchronous Colon Adenocarcinoma With Right Inguinal Lymph Node Metastasis: A Case Report and Brief Literature Review

Alzahrani

Alshehri

2020

Cureus

View full text Add to dashboard Cite

Colon cancer is one of the common cancers and a major reason for cancer-related deaths with reported metastasis to the lungs and liver. Metastasis to inguinal lymph nodes from the adenocarcinoma of the colon is very rare and needs to be managed distinctly. We present a case of moderately differentiated adenocarcinoma of colon confirmed pathologically in an elderly male patient with locally extensive malignancy with involvement of the right-sided inguinal lymph nodes.

show abstract

“…Although there were a few reports on external iliac or inguinal lymph node metastasis of colon cancer, these cases had regional lymph node metastasis [ 16 – 19 ]. Uehara et al proposed one hypothesis for this rare pattern of lymphatic metastasis.…”

Section: Discussionmentioning

confidence: 99%

Ascending colon cancer with synchronous external iliac and inguinal lymph node metastases but without regional lymph node metastasis: a case report and brief literature review

et al. 2017

View full text Add to dashboard Cite

Lymph node metastasis to the iliac or inguinal region of colon cancer is extremely rare. We experienced a case of ascending colon cancer with synchronous isolated right external iliac and inguinal lymph node metastases but without any regional lymph node metastasis. An 83-year-old woman was admitted to our hospital due to anemia. Colonoscopy and computed tomography revealed an ascending colon cancer and also right external iliac and inguinal lymph node swelling. Further examination by F-deoxyglucose positron emission tomography strongly suggested that these lymph nodes were metastatic. Right hemicolectomy with lymph node dissection along the superior mesenteric artery, and right external iliac and inguinal lymph node dissection were performed. Histological examination revealed that both lymph nodes were metastasized from colon cancer, and there was no evidence of regional lymph node metastasis. The patient has shown no sign of recurrence at 27 months after surgery.

show abstract

Inguinal lymphadenopathy secondary to adenocarcinoma of caecum: A case report

Cited by 10 publications

References 11 publications

Metachronous metastasis to inguinal lymph nodes from sigmoid colon adenocarcinoma with abdominal wall metastasis: a case report

Metachronous metastasis to inguinal lymph nodes from sigmoid colon adenocarcinoma with abdominal wall metastasis: a case report

Synchronous Colon Adenocarcinoma With Right Inguinal Lymph Node Metastasis: A Case Report and Brief Literature Review

Ascending colon cancer with synchronous external iliac and inguinal lymph node metastases but without regional lymph node metastasis: a case report and brief literature review

Contact Info

Product

Resources

About