2015
DOI: 10.1038/jes.2015.77
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Inhalation cancer risk assessment of hexavalent chromium based on updated mortality for Painesville chromate production workers

Abstract: The exposure-response for hexavalent chromium (Cr(VI))-induced lung cancer among workers of the Painesville Ohio chromate production facility has been used internationally for quantitative risk assessment of environmental and occupational exposures to airborne Cr(VI). We updated the mortality of 714 Painesville workers (including 198 short-term workers) through December 2011, reconstructed exposures, and conducted exposure-response modeling using Poisson and Cox regressions to provide quantitative lung cancer … Show more

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Cited by 56 publications
(40 citation statements)
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“…Studies in languages other than English were included if they met the inclusion criteria. If multiple studies were published on the same cohort population, the most recent/updated results were included (Langard 1990;Lipworth et al 2011;Gibb et al 2015;Proctor et al 2016). Proportionate mortality ratio (PMR) and proportionate cancer mortality ratio (PCMR) studies were excluded-it is widely acknowledged that these types of studies are difficult to interpret, because they cannot measure risks or rates due to lacking population denominator data (Aschengrau and Seage 2003;Rothman et al 2008;Guha et al 2010).…”
Section: Literature Searchmentioning
confidence: 99%
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“…Studies in languages other than English were included if they met the inclusion criteria. If multiple studies were published on the same cohort population, the most recent/updated results were included (Langard 1990;Lipworth et al 2011;Gibb et al 2015;Proctor et al 2016). Proportionate mortality ratio (PMR) and proportionate cancer mortality ratio (PCMR) studies were excluded-it is widely acknowledged that these types of studies are difficult to interpret, because they cannot measure risks or rates due to lacking population denominator data (Aschengrau and Seage 2003;Rothman et al 2008;Guha et al 2010).…”
Section: Literature Searchmentioning
confidence: 99%
“…EPA 2010;OEHHA 2011;ATSDR 2012;IARC 2012;NIOSH 2013;Welling et al 2015) to identify studies missed by the electronic search and title and abstract screening. Seven studies were included based on hand searching and full text review (Moulin et al 1990(Moulin et al , 1992Moulin et al 1995;Sorahan and Harrington 2000;Smailyte et al 2004;Proctor et al 2016).…”
Section: Category Detailsmentioning
confidence: 99%
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