2013
DOI: 10.1111/jsap.12133
|View full text |Cite
|
Sign up to set email alerts
|

Inhaled budesonide therapy in cats with naturally occurring chronic bronchial disease (feline asthma and chronic bronchitis)

Abstract: Treatment with inhaled budesonide was well tolerated, resulting in improvement of clinical signs and barometric whole body plethysmography parameters. Although inhaled budesonide therapy was found to cause suppression of the hypothalamic-pituitary-adrenal axis in some cats, no cats showed clinical signs attributable to corticosteroid side effects.

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
3
1
1

Citation Types

3
34
1
18

Year Published

2015
2015
2025
2025

Publication Types

Select...
5
2
1

Relationship

0
8

Authors

Journals

citations
Cited by 30 publications
(56 citation statements)
references
References 19 publications
3
34
1
18
Order By: Relevance
“…Ophthalmic instillation of 1% prednisolone acetate or 0.1% dexamethasone four times daily in both eyes resulted in HPA axis suppression within 2 weeks, intensifying throughout the treatment period (Roberts et al, 1984;Glaze et al, 1988). Inhalant budesonide in cats with chronic bronchial disease resulted in HPA axis suppression in three of 15 cases (Galler et al, 2013). The new generation of topical steroids cause minimal signs of iatrogenic hyperadrenocorticism but are associated with HPA axis suppression.…”
Section: Alteration Of the Hypothalamic Pituitary Adrenal Axismentioning
confidence: 98%
See 1 more Smart Citation
“…Ophthalmic instillation of 1% prednisolone acetate or 0.1% dexamethasone four times daily in both eyes resulted in HPA axis suppression within 2 weeks, intensifying throughout the treatment period (Roberts et al, 1984;Glaze et al, 1988). Inhalant budesonide in cats with chronic bronchial disease resulted in HPA axis suppression in three of 15 cases (Galler et al, 2013). The new generation of topical steroids cause minimal signs of iatrogenic hyperadrenocorticism but are associated with HPA axis suppression.…”
Section: Alteration Of the Hypothalamic Pituitary Adrenal Axismentioning
confidence: 98%
“…The insertion of a 16α-hydroxy group decreases mineralocorticoid activity and leads to the synthesis of triamcinolone (which also has a 9α-fluoro group). In particular the use of budesonide as an oral drug for the treatment of inflammatory bowel disease and budesonide and fluticasone propionate as inhaled medications for chronic inflammatory airway disease has recently gained popularity in dogs and cats (Bexfield et al, 2006;Padrid, 2006;Dye et al, 2013;Galler et al, 2013;Pietra et al, 2013). The effects of glucocorticoids are dose dependent, and they are classified according to their potency in relation to the potency of cortisol (Table 14-1).…”
Section: Chemistry Of Glucocorticoids and Structure-activity Relationmentioning
confidence: 99%
“…Bei manchen Tieren war bei hoher Dosis (400 µg 2 × tgl.) nach 2 Monaten eine Unterdrückung der HHNA nachweisbar, jedoch ohne klinische Symptomatik [85]. Das Gleiche zeigte sich bei der inhalativen Anwendung von Flunisolid [85] [86].…”
Section: Inhalativ Verabreichte Glukokortikoideunclassified
“…nach 2 Monaten eine Unterdrückung der HHNA nachweisbar, jedoch ohne klinische Symptomatik [85]. Das Gleiche zeigte sich bei der inhalativen Anwendung von Flunisolid [85] [86]. Auch bei Katzen mit CB konnte die Entzündungsaktivität in den unteren Atemwegen durch Inhalation mit Fluticason signifikant reduziert werden [87].…”
Section: Inhalativ Verabreichte Glukokortikoideunclassified
“…3 mg/m 2 ) (31,86,91). Inhalativ appliziertes Budesonid zeigte bei Katzen mit chronisch entzündlichen Bronchialerkrankungen eine gute Verträglichkeit und Effektivität (36).…”
Section: Glukokortikoideunclassified