Inhaled nitrous oxide for painful procedures in children and youth: a systematic review and meta-analysis

Poonai, Naveen; Creene, Christopher; Dobrowlanski, Ariel; Geda, Rishika; Hartling, Lisa; Ali, Samina; Bhatt, Maala; Trottier, Evelyne D.; Sabhaney, Vikram; O’Hearn, Katie; Jain, Rini; Osmond, Martin H.

doi:10.1007/s43678-023-00507-0

Cited by 6 publications

(2 citation statements)

References 61 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Patients need to be monitored while under anesthesia with nitrous oxide by a staff member who is trained in basic airway management [45]. A recent meta-analysis found nitrous oxide to be more effective in reducing pain related to laceration repair than subcutaneous lidocaine, oral midazolam, and oxygen [48 ▪ ].…”

Section: Minimal To Moderate Procedural Sedation Techniquesmentioning

confidence: 99%

Strategies to minimize procedure-related pain and anxiety: lessons from pediatric dermatology

Abouchaleh,

Bayart

2024

Current Opinion in Pediatrics

View full text Add to dashboard Cite

Purpose of review Recent studies have suggested that prolonged or repeated episodes of general anesthesia early in childhood may adversely affect neurodevelopment. This, combined with rising healthcare costs and decreasing access, has sparked interest in performing pediatric procedures in the office setting when possible. It is essential to address the physical and psychological discomfort that often accompany this experience, particularly in children. Recent findings Healthcare providers performing procedures on children can draw from a spectrum of established techniques, new technology, and novel use of medications to decrease peri-procedural pain and anxiety. These techniques include distraction, optimization of local anesthesia, and mild to moderate sedation. Summary We recommend using a combination of techniques to minimize pain and anxiety to improve safety, decrease healthcare costs, improve patient experience, and prevent childhood trauma and persistent negative perception of the healthcare system.

show abstract

Section: Minimal To Moderate Procedural Sedation Techniquesmentioning

confidence: 99%

Strategies to minimize procedure-related pain and anxiety: lessons from pediatric dermatology

Abouchaleh,

Bayart

2024

Current Opinion in Pediatrics

View full text Add to dashboard Cite

show abstract

“…Attention should also be paid to patients that receive CYP3A4 inducers, such as carbamazepine. In this case, the analgesic effect of FE can be significantly reduced [ 137 ].…”

Section: Treatment Of Pediatric Painmentioning

confidence: 99%

Pain Management in Children Admitted to the Emergency Room: A Narrative Review

Cunico,

Rossi,

Verdesca

et al. 2023

Pharmaceuticals

View full text Add to dashboard Cite

Pain is a biopsychosocial experience characterized by sensory, physiological, cognitive, affective, and behavioral components. Both acute and chronic pain can have short and long-term negative effects. Unfortunately, pain treatment is often inadequate. Guidelines and recommendations for a rational approach to pediatric pain frequently differ, and this may be one of the most important reasons for the poor attention frequently paid to pain treatment in children. This narrative review discusses the present knowledge in this regard. A literature review conducted on papers produced over the last 8 years showed that although in recent years, compared to the past, much progress has been made in the treatment of pain in the context of the pediatric emergency room, there is still a lot to do. There is a need to create guidelines that outline standardized and easy-to-follow pathways for pain recognition and management, which are also flexible enough to take into account differences in different contexts both in terms of drug availability and education of staff as well as of the different complexities of patients. It is essential to guarantee an approach to pain that is as uniform as possible among the pediatric population that limits, as much as possible, the inequalities related to ethnicity and language barriers.

show abstract

Nitrous oxide use in Canadian pediatric emergency departments: a survey of physician’s knowledge, attitudes, and practices

Jain,

Hudson,

Osmond

et al. 2023

Can J Emerg Med

View full text Add to dashboard Cite

Inhaled nitrous oxide for painful procedures in children and youth: a systematic review and meta-analysis

Cited by 6 publications

References 61 publications

Strategies to minimize procedure-related pain and anxiety: lessons from pediatric dermatology

Strategies to minimize procedure-related pain and anxiety: lessons from pediatric dermatology

Pain Management in Children Admitted to the Emergency Room: A Narrative Review

Nitrous oxide use in Canadian pediatric emergency departments: a survey of physician’s knowledge, attitudes, and practices

Contact Info

Product

Resources

About