Inheritance of Color, Beard, Tassels and Horns in the Goat

Asdell, S. A.; Smith, A. D. Buchanan

doi:10.1093/oxfordjournals.jhered.a103037

Cited by 17 publications

(18 citation statements)

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“…The beard (Br) locus has the alleles bearded "b" and wild "+" (Asdell and Buchanan-Smith, 1928;COGNOSAG, 1986). Only females were considered in the allelic frequency calculation.…”

Section: Consideration Of Traits and Allelesmentioning

confidence: 99%

Genetic distances and taxonomic trees between goats of Ceará State (Brazil) and goats of the Mediterranean region (Europe and Africa)

2000

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Goats of an undefined breed (called UDB) from the State of Ceará, northeastern Brazil (N = 447), European Mediterranean goats (N = 3,847) and African Mediterranean goats (N = 325) were compared to establish genetic distances and taxonomic trees. Allelic frequencies in each population for presence or absence of the following traits were used: horns, reduced ears, long hair, wattles, beard, roan color, brown eumelanin and eumelanic standard pigmentation. The genetic distance, applying the method developed by Nei (1972), was: least between goats from different meso-regions of the State of Ceará (0.0008 to 0.0120); small between all UDB of Ceará and French goats of Rove and Haute Roya (0.0236 and 0.0459); greater between all UDB of Ceará and northern Spanish goats (0.1166), and greatest between all UDB of Ceará and northern African goats (Moroccan of Drâa, Rhâali and Zagora), Balkan goats (Sakhar from Bulgaria and Macedonia from Greece) and some insular Mediterranean populations (Corsica, Sicily and Sardinia), which ranged from 0.1237 to 0.2714. Brazilian UDB goats are more closely related to Continental and Western European populations than to North African, Balkan or Insular Mediterranean populations.

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“…The beard (Br) locus has the alleles bearded "b" and wild "+" (Asdell and Buchanan-Smith, 1928;COGNOSAG, 1986). Only females were considered in the allelic frequency calculation.…”

Section: Consideration Of Traits and Allelesmentioning

confidence: 99%

Genetic distances and taxonomic trees between goats of Ceará State (Brazil) and goats of the Mediterranean region (Europe and Africa)

2000

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“…In this species, the effect of the Agouti locus on coat color and color pattern distribution has been proposed by several authors who analyzed herd book records and segregation data within breeds or from experimental populations [Lush, 1926;Asdell and Buchanan Smith, 1928;Ricordeau and Lauvergne, 1971;Lauvergne, 1978;Lauvergne et al, 1987;Adalsteinsson et al, 1994;Sponenberg et al, 1998]. From these studies, a series of about 20 alleles, some of which probably overlap, has been deduced.…”

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confidence: 99%

Copy Number Variation and Missense Mutations of the Agouti Signaling Protein (<i>ASIP)</i> Gene in Goat Breeds with Different Coat Colors

Fontanesi

Beretti

Riggio

et al. 2009

Cytogenet Genome Res

132

121

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In goats, classical genetic studies reported a large number of alleles at the Agouti locus with effects on coat color and pattern distribution. From these early studies, the dominant A^Wt (white/tan) allele was suggested to cause the white color of the Saanen breed. Here, we sequenced the coding region of the goat ASIP gene in 6 goat breeds (Girgentana, Maltese, Derivata di Siria, Murciano-Granadina, Camosciata delle Alpi, and Saanen), with different coat colors and patterns. Five single nucleotide polymorphisms (SNPs) were identified, 3 of which caused missense mutations in conserved positions of the cysteine-rich carboxy-terminal domain of the protein (p.Ala96Gly, p.Cys126Gly, and p.Val128Gly). Allele and genotype frequencies suggested that these mutations are not associated or not completely associated with coat color in the investigated goat breeds. Moreover, genotyping and sequencing results, deviation from Hardy-Weinberg equilibrium, as well as allele copy number evaluation from semiquantitative fluorescent multiplex PCR, indicated the presence of copy number variation (CNV) in all investigated breeds. To confirm the presence of CNV and evaluate its extension, we applied a bovine-goat cross-species array comparative genome hybridization (aCGH) experiment using a custom tiling array based on bovine chromosome 13. aCGH results obtained for 8 goat DNA samples confirmed the presence of CNV affecting a region of less that 100 kb including the ASIP and AHCY genes. In Girgentana and Saanen breeds, this CNV might cause the A^Wt allele, as already suggested for a similar structural mutation in sheep affecting the ASIP and AHCY genes, providing evidence for a recurrent interspecies CNV. However, other mechanisms may also be involved in determining coat color in these 2 breeds.

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“…Early works include those of Asdell and Buchanan Smith (1928) and Eidregevic (1941), who concluded that brown was dominant to black. This was further substantiated by Hards (1950).…”

Section: Introductionmentioning

confidence: 99%