2024
DOI: 10.1111/nyas.15130
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Inherited physical capacity: Widening divergence from young to adult to old

Ole J. Kemi,
Morten A. Hoydal,
Per M. Haram
et al.

Abstract: Cardiorespiratory performance segregates into rat strains of inherited low‐ and high‐capacity runners (LCRs and HCRs); during adulthood, this segregation remains stable, but widens in senescence and is followed by segregated function, health, and mortality. However, this segregation has not been investigated prior to adulthood. We, therefore, assessed cardiorespiratory performance and cardiac cell (cardiomyocyte) structure–function in 1‐ and 4‐month‐old LCRs and HCRs. Maximal oxygen uptake was 23% less in LCRs… Show more

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