Inhibition and enhancement by organic compounds of luminol–KIO4–H2O2 chemiluminescence

Hong, Xu; Duan, Chunfeng; Lai, Chaohua; Lian, Mei; Zhang, Zhifeng; Liu, Lijuan; Cui, Hua

doi:10.1002/bio.905

Cited by 28 publications

(11 citation statements)

References 14 publications

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“…The activity of a chemical enhancer, which is the most attractive mode for increasing the sensitivity, is strongly dependant upon pH of the CL reaction system [41,42]. Therefore, the effect of pH on CL reaction of L-012 was investigated.…”

Section: Optimization Of CL Conditionsmentioning

confidence: 99%

An ultrasensitive and highly selective determination method for quinones by high-performance liquid chromatography with photochemically initiated luminol chemiluminescence

Ahmed

Kishikawa

Ohyama

et al. 2009

Journal of Chromatography A

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Quinones are a class of compounds of substantial toxicological and pharmacological interest. An ultrasensitive and highly selective chemiluminescence (CL) method was newly developed for the determination of quinones based on the utility of photochemically initiated luminol CL. The method involves ultraviolet (UV) irradiation of quinones to generate reactive oxygen species (ROS) through the unique photosensitization reaction accompanied with the photolytical generation of 3,6-dihydroxyphthalic acid (DHPA) from quinones. The photoproducts were detected by luminol CL reaction. Interestingly, it was noticed that DHPA had enhancement effect for the luminol CL. The generation of the enhancer (DHPA) in association with the oxidant (ROS) in the photochemical reaction greatly increases the sensitivity and selectivity of the proposed luminol CL method. In order to elucidate the type of ROS produced by the photosensitizaion reaction in relation to the proposed CL reaction, we investigated the quenching effect of selective ROS scavengers in the luminol CL. Although several ROS were generated, superoxide anion was the most effective ROS for the generated CL. Moreover, the enhancement mechanism of DHPA for luminol CL was confirmed. The enhancement was found to be through the formation of stabilized semiquinone anion radical that provided long-lived CL. The generation of the semiquinone radical was confirmed by electron spin resonance technique. Furthermore, we developed an HPLC method with on-line photochemical reaction followed by the proposed CL detection for the determination of four quinones. A luminol analogue, L-012, was used for its high sensitivity. The detection limits for quinones obtained with the proposed method (S/N=3) were in the range 1.5-24 fmol that were 10-1000 times more sensitive compared with the previous methods. Finally, the developed HPLC-CL system was successfully applied for the determination of quinones in airborne particulate samples collected at Nagasaki city.

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Section: Optimization Of CL Conditionsmentioning

confidence: 99%

An ultrasensitive and highly selective determination method for quinones by high-performance liquid chromatography with photochemically initiated luminol chemiluminescence

Ahmed

Kishikawa

Ohyama

et al. 2009

Journal of Chromatography A

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“…Nevertheless, the light absorption of the mixed system was not equal to the sum of the light absorption of the two individual systems, which implied that citrate might be involved in the cerium(IV)-Tween 85-organic compound reaction system. Based on the above discussion, Tween 85, organic compounds and citrate were oxidized by cerium(IV) in sulfuric acid medium, which emitted a characteristic radiation corresponding to the peak at 478 nm (30,(41)(42)(43). We presumed that when phenolic compounds, such as salicylic acid or 2,4-dihydroxybenzoic acid, were injected into the system, they would be partially converted to quinone, which could be the reason why enhancing peaks appear simultaneously in CL kinetic curves for some phenolic acids.…”

Section: Possible Chemiluminescence Mechanism Discussionmentioning

confidence: 99%

Enhanced chemiluminescence of cerium(IV)–Tween 85 system and the analytical application

Zhu

et al. 2012

Luminescence

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The oxidation reaction between cerium(IV) and Tween 85 in sulfuric acid medium produced weak chemiluminescence (CL). In this paper, it was found that citrate could strongly enhance the CL of cerium(IV)-Tween 85-polyphenol system. Based on studies of ultraviolet-visible spectra and CL spectra, the CL enhancement mechanism had been proposed. It was surmised that the light emission was from an excited oxygen molecular pair O2((1)Δg)O2((1)∑g(-)). The maximum emission wavelength was about 478 nm. The effects of 17 amino acids and 29 organic compounds on cerium(IV)-Tween 85-citrate CL were investigated by a flow injection procedure. This study showed the present system had a wide application for the determination of these compounds.

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“…(acceptor), which produced HCNs ⁎ [40], and a strong light emission obtained when the HCNs ⁎ returned back to its ground state level. Furthermore, the •O 2 -were competitively consumed by DHZS, a 1,4-dihydrazinophthalazine sulfate, leading to the decrease of HCNs* and inhibition of CL intensity [29,41].…”

Section: Samplesmentioning

confidence: 99%

Determination of dihydralazine based on chemiluminescence resonance energy transfer of hollow carbon nanodots

Han

Fan

Chen

et al. 2017

Spectrochimica Acta Part A: Molecular and Biomolecular Spectros

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Inhibition and enhancement by organic compounds of luminol–KIO₄–H₂O₂ chemiluminescence

Cited by 28 publications

References 14 publications

An ultrasensitive and highly selective determination method for quinones by high-performance liquid chromatography with photochemically initiated luminol chemiluminescence

An ultrasensitive and highly selective determination method for quinones by high-performance liquid chromatography with photochemically initiated luminol chemiluminescence

Enhanced chemiluminescence of cerium(IV)–Tween 85 system and the analytical application

Determination of dihydralazine based on chemiluminescence resonance energy transfer of hollow carbon nanodots

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