Inhibition of acetylcholinesterases by pulegone-1,2-epoxide

Grundy, Dawn L.; Still, Cecil C.

doi:10.1016/0048-3575(85)90100-2

Cited by 111 publications

(70 citation statements)

References 9 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…AChE is a key enzyme that terminates nerve impulses by catalyzing the hydrolysis of neurotransmitter, acetylcholine, in the nervous system in various organisms (Oehmichen and Besserer 1982;Grundy and Still 1985;Wang et al 2004). In this study, A. annua extract inhibited the AChE activity in higher doses which coincided with other reports about effect of botanical insecticides on AChE inhibition.…”

Section: Discussionsupporting

confidence: 75%

A Study on the Toxicity of a Medicinal Plant, Artemisia Annua L. (Asteracea) Extracts to the Sunn Pest, Eurygaster Integriceps Puton (Hemiptera: Scutelleridae)

Zibaee

Bandani²

2010

Journal of Plant Protection Research

View full text Add to dashboard Cite

Abstract:A methanolic extract of Artemisia annua was obtained to evaluate its insecticidal activities against the sunn pest (Eurygaster intefriceps). Also, the responses of general esterase (EST), glutathione S-transferase (GST), alkaline phosphatase (ALP), acid phosphatase (ACP), acethylcholinesterase (AChE) to the plant extract were investigated. Topical application of plant extract on adults showed that the mortality was dose-dependent i.e. with increasing of plant extract concentrations more mortality achieved. Esterase and GST activities were increased in the first 24 h post-treatment. However, the enzymes activities were decreased after 24 h until 72 h. The activities of ALP, ACP and AChE in insect body decreased significantly and inhibition was higher along with increasing concentrations of plant extract. Isozyme electrophoresis profiles indicated that responses of isozymes (EST and GST) to plant extract were decreased after 48 h exposure to extract so that some enzymes bands disappeared. The results indicated that the highest concentration of A. annua extract was the most toxic among the four extracts. The decline of the detoxification ability in insects' tissues might be the main reason for the insecticidal activities.

show abstract

Section: Discussionsupporting

confidence: 75%

A Study on the Toxicity of a Medicinal Plant, Artemisia Annua L. (Asteracea) Extracts to the Sunn Pest, Eurygaster Integriceps Puton (Hemiptera: Scutelleridae)

Zibaee

Bandani²

2010

Journal of Plant Protection Research

View full text Add to dashboard Cite

show abstract

“…It has been reported that monoterpenes were effective inhibitors of acetylcholinesterases (AChEs) from eels, houseflies, and bovine erythrocytes (Gracza 1985;Grundy and Still, 1985;Miyazawa et al, 1997;Ryan and Byrne, 1998;Picollo et al, 2008); however, Lee et al (2001) and Abdelgaleil et al (2009) reported that monoterpene toxicity was not necessarily correlated with the ability to inhibit AChE activity. Another researcher has demonstrated that some monoterpenes bind to octopamine receptors (Enan, 2001).…”

Section: Discussionmentioning

confidence: 99%

Molluscicidal and insecticidal potential of monoterpenes on the white garden snail, Theba pisana (Muller) and the cotton leafworm, Spodoptera littoralis (Boisduval)

Abdelgaleil

2010

Appl. Entomol. Zool.

View full text Add to dashboard Cite

“…Asian varieties of A. calamus contain varying amounts of beta-asarone and cause sedative effects when ingested, and also possess anti-gonadal activity against some insect species (Saxena et al, 1977;Schmidt and Brochers, 1981). Monoterpene hydrocarbons, also an active component of sweet flag, are competitive inhibitors of 245 Insecticidal Activity of Acorus calamus acetylcholinesterases, which are neurotoxic to insects (Grundy and Still, 1985;Miyazawa et al, 1997). The use of individual active components of A. calamus under field conditions would not be desirable because the insect may easily develop resistance.…”

Section: Discussionmentioning

confidence: 99%

Efficacy of Acorus calamus L. leaves and rhizome on mortality and reproduction of Callosobruchus chinensis L. (Coleoptera: Bruchidae)

Shukla

Kumar

Prasad

et al. 2009

Appl. Entomol. Zool.

View full text Add to dashboard Cite

Laboratory and field experiments were conducted to investigate the bioefficacy of sweet flag (Acorus calamus) against the pulse beetle Callosobruchus chinensis, which infests stored chick pea seeds. Dried powders of the leaf and rhizome as well as their extracts in methanol (ME) and petroleum ether (PEE) were evaluated as bio-insecticides against the beetle. Rhizome powder (5 mg/g seed) was found to be more efficacious, causing 100% mortality, than leaf powder (20 mg/g seed), showing 91.1% mortality. Rhizome powders also showed 100% ovicidal activity and thus completely inhibited F 1 emergence at a lower dose than that of leaf powders. The ME and PEE of leaves and rhizome showed 12 to 100% mortality. The percentage of egg laying decreased from 12.8 to 100 with increasing doses of powders and extracts. No F 1 adult emerged at 0.3-0.4 mg/g ME of leaves and rhizome and PEE of rhizome. In six-month field trials, all treatments at laboratory doses proved efficacious (75-98%) over organophosphate insecticide malathion (74.4%) in terms of feeding deterrence. Powder-and extract-treated chick pea seeds did not lose their viability and germinated at 100%, similar to control seeds. It was concluded that leaf and rhizome powders and their solvent extracts showed significant mortality, and inhibition of egg laying and F 1 emergence of C. chinensis at varying concentrations. Hence, the leaves and rhizome of A. calamus may be recommended as admixtures in the integrated management of beetle infestation of pulse seeds during storage.

show abstract

Inhibition of acetylcholinesterases by pulegone-1,2-epoxide

Cited by 111 publications

References 9 publications

A Study on the Toxicity of a Medicinal Plant, Artemisia Annua L. (Asteracea) Extracts to the Sunn Pest, Eurygaster Integriceps Puton (Hemiptera: Scutelleridae)

A Study on the Toxicity of a Medicinal Plant, Artemisia Annua L. (Asteracea) Extracts to the Sunn Pest, Eurygaster Integriceps Puton (Hemiptera: Scutelleridae)

Molluscicidal and insecticidal potential of monoterpenes on the white garden snail, Theba pisana (Muller) and the cotton leafworm, Spodoptera littoralis (Boisduval)

Efficacy of Acorus calamus L. leaves and rhizome on mortality and reproduction of Callosobruchus chinensis L. (Coleoptera: Bruchidae)

Contact Info

Product

Resources

About