1989
DOI: 10.1016/0165-1218(89)90077-3
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Inhibition of clastogenic effect of radiation by Liv. 52 in the bone marrow of mice

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Cited by 20 publications
(20 citation statements)
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“…DOI 10.1002/em frequency of radiation-induced micronuclei in the PCEs and NCEs. This inhibition is in agreement with an earlier report on the inhibition of radiation-induced micronucleus formation by Liv 52 in mouse myeloblasts [Jagetia and Ganapathi, 1989] and the inhibition of micronuclei in mouse bone marrow erythrocytes by abana, another herbal preparation [Jagetia and Aruna, 1997]. Extracts of Spirulina platensis, Phyllanthus niruri, Moringa oleifera, Syzygium cumini, and Aegle marmelos also have been reported to inhibit radiation-induced micronucleus formation in vivo and in vitro [Qishen et al, 1989;Uma Devi et al, 2000;Rao et al, 2001;Jagetia and Baliga, 2002a;.…”
Section: Discussionsupporting
confidence: 94%
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“…DOI 10.1002/em frequency of radiation-induced micronuclei in the PCEs and NCEs. This inhibition is in agreement with an earlier report on the inhibition of radiation-induced micronucleus formation by Liv 52 in mouse myeloblasts [Jagetia and Ganapathi, 1989] and the inhibition of micronuclei in mouse bone marrow erythrocytes by abana, another herbal preparation [Jagetia and Aruna, 1997]. Extracts of Spirulina platensis, Phyllanthus niruri, Moringa oleifera, Syzygium cumini, and Aegle marmelos also have been reported to inhibit radiation-induced micronucleus formation in vivo and in vitro [Qishen et al, 1989;Uma Devi et al, 2000;Rao et al, 2001;Jagetia and Baliga, 2002a;.…”
Section: Discussionsupporting
confidence: 94%
“…DOI 10.1002/em 1981; Uma Devi and Bisht, 1987;Jagetia and Ganapathi, 1989;Uma Devi and Prasanna, 1990;Jagetia and Aruna, 1997]. Brezani et al [1982] reported increased bone marrow MPCE frequencies at 9-12 hr and at 37-39 hr after exposure of mice to various doses of g-irradiation.…”
Section: Discussionmentioning
confidence: 94%
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“…This may be due to the presence of constituents that could interact and stimulate the formation and the secretion of erythropoietin and the haematopoietic growth factors/committed stem cells [30]. Our results are concurrent with the findings of the studies which were done on other plant extracts, which have been reported elsewhere [31][32][33][34][35][36][37].…”
Section: Discussionsupporting
confidence: 82%
“…The herbal preparation Liv. 52, which has been widely used to treat liver disorders, has been reported to protect mice against radiation-induced sickness, mortality, dermatitis, spleen injury, liver damage, decrease in the peripheral blood cell counts, prenatal development and radiationinduced chromosome damage (Saini et al , 1984a,b;Jagetia and Ganapathi, 1989;. Certain other herbal preparations like brahmarasayana, narasimharasayana, ashwagandharasayana, and amrithaprasham, a group of herbal preparations used to improve the general health, have also been reported to reduce the radiationinduced lipid peroxidation in the liver, and leucopenia in mice (Kumar et al , 1996).…”
Section: Introductionmentioning
confidence: 99%