Inhibition of leukocyte-type 12-lipoxygenase by guava tea leaves prevents development of atherosclerosis

Takahashi, Yoshitaka; Otsuki, Akemi; Mori, Yoshiko; Kawakami, Yuki; Ito, Hideyuki

doi:10.1016/j.foodchem.2015.03.105

Cited by 12 publications

(3 citation statements)

References 33 publications

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“…In fact, the effect was connected to the presence of ethyl gallate and quercetin [121,122]. In streptozotocin-induced diabetic rats, vascular reactivity to vasoconstrictor agents was reduced, as was vessel atherosclerosis [112].…”

Section: Pharmacological Propertiesmentioning

confidence: 99%

Health Effects of Psidium guajava L. Leaves: An Overview of the Last Decade

Díaz‐de‐Cerio

Verardo

Gómez-Caravaca

et al. 2017

IJMS

140

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Today, there is increasing interest in discovering new bioactive compounds derived from ethnomedicine. Preparations of guava (Psidium guajava L.) leaves have traditionally been used to manage several diseases. The pharmacological research in vitro as well as in vivo has been widely used to demonstrate the potential of the extracts from the leaves for the co-treatment of different ailments with high prevalence worldwide, upholding the traditional medicine in cases such as diabetes mellitus, cardiovascular diseases, cancer, and parasitic infections. Moreover, the biological activity has been attributed to the bioactive composition of the leaves, to some specific phytochemical subclasses, or even to individual compounds. Phenolic compounds in guava leaves have been credited with regulating blood-glucose levels. Thus, the aim of the present review was to compile results from in vitro and in vivo studies carried out with guava leaves over the last decade, relating the effects to their clinical applications in order to focus further research for finding individual bioactive compounds. Some food applications (guava tea and supplementary feed for aquaculture) and some clinical, in vitro, and in vivo outcomes are also included.

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Section: Pharmacological Propertiesmentioning

confidence: 99%

Health Effects of Psidium guajava L. Leaves: An Overview of the Last Decade

Díaz‐de‐Cerio

Verardo

Gómez-Caravaca

et al. 2017

IJMS

140

View full text Add to dashboard Cite

show abstract

“…In the treatment of diarrhea in children, it is important to pay attention to adequate hydration so that the child does not become dehydrated. Apart from that, there are various natural methods that can help overcome the symptoms of diarrhea in children, one of which is using the guava plant (Akila et al, 2018;Takahashi et al, 2015).…”

Section: Introductionmentioning

confidence: 99%

Health secrets hidden in guava leaves: Guava tea, a delicious and natural solution to treat diarrhea in children!

Vaidyanatahan,

Sidiq,

Halim

2023

IJRCS

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This study aims to increase public knowledge about the processing of guava leaves as herbal medicine to treat diarrhea. Prior to counseling and training, the results of the pretest showed that most of the participants (70.5%) had known the utilization and processing of guava leaves as herbal medicine. After attending the training, participants were given a post-test questionnaire to measure the increase in their knowledge.The results showed that there was a significant increase in the participants' knowledge after attending the training. The knowledge percentage increased from 70.5% to 89.0%, representing an increase of 18.5%. This training provides information on how to process guava leaves into herbal medicines that are effective in treating diarrhea.Some of the processing methods taught in the training include making guava leaf tea, guava leaf extract, and decoction of guava leaves. Participants were also given knowledge about the active ingredients in guava leaves, such as quercetin, which has an anti-diarrhea effect.This study showed that the counseling and training program was effective in increasing participants' knowledge about processing guava leaves as a herbal medicine to treat diarrhea. With the knowledge gained, it is hoped that the community can properly process guava leaves and use them effectively in maintaining health and treating diarrhea with simple medication. This program also empowers garden plants in the environment around the village as an easily accessible source of herbal medicines.

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“…The leaves are rich in functional components. Guava is an edible fruit whose leaf is widely used in tea and drinks [13] and is also recognized as a high-quality medical material in the world, which is now widely cultivated in southern China [14]. Diseases have continuously and significantly impacted crop yield.…”

Section: Introductionmentioning

confidence: 99%

An Efficient Approach for Separating Essential Oil and Polysaccharides Simultaneously from Fresh Leaves of Guajava by Microwave-Mediated Hydrodistillation with Lithium Salts and Antibacterial Activity of Essential Oil

et al. 2022

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The essential oils and polysaccharides from guava leaves have important functions. In the process of microwave extraction of plant essential oils and polysaccharides, pretreatment with lithium salts solution is helpful to increase the extraction rate. The experiment was conducted using a single factor method. Results were optimized by principal component analysis and response surface optimization. The optimal conditions were: LiCl dosage 45 μmol, microwave time 40 min, liquid-solid ratio 10, homogenization time 4.2 min, liquid-material ratio 10, and microwave irradiation power 700 W. The highest yield of essential oil and polysaccharide were 10.27 ± 0.58 mL/kg dry weight (DW) and 50.31 ± 1.88 g/kg·DW, respectively. Three verification experiments showed that the extraction rate of the microwave method was higher than that of the traditional heating method. In addition, the bacteriostatic zones reached the maximum 23.7 ± 0.11 mm when the concentration was 40 μL/mL, and the above results have practical significance.

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Inhibition of leukocyte-type 12-lipoxygenase by guava tea leaves prevents development of atherosclerosis

Cited by 12 publications

References 33 publications

Health Effects of Psidium guajava L. Leaves: An Overview of the Last Decade

Health Effects of Psidium guajava L. Leaves: An Overview of the Last Decade

Health secrets hidden in guava leaves: Guava tea, a delicious and natural solution to treat diarrhea in children!

An Efficient Approach for Separating Essential Oil and Polysaccharides Simultaneously from Fresh Leaves of Guajava by Microwave-Mediated Hydrodistillation with Lithium Salts and Antibacterial Activity of Essential Oil

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