EXCLI Journal; 19:Doc613; ISSN 1611-2156 2020
DOI: 10.17179/excli2020-1331
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Inhibition of prostate cancer cell line (PC-3) by anhydrodihydroartemisinin (ADHA) through caspase-dependent pathway

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“…Brucine inhibited the expression of HSP70 and promoted the apoptosis of PC-3 cells ( Yan et al, 2022 ). Artemisinin inhibited c-Jun, p-c-Jun, NF-κB, p-Akt, caused PC-3 cell death via caspase-dependent intrinsic signaling cascade ( Ahmad et al, 2020 ). Wogonoside inhibited PC-3 cell viability, migration, and invasion by suppressing Wnt/ β -catenin pathway and reversing EMT ( Wei et al, 2019 ).…”
Section: Experimental Researchmentioning
confidence: 99%
“…Brucine inhibited the expression of HSP70 and promoted the apoptosis of PC-3 cells ( Yan et al, 2022 ). Artemisinin inhibited c-Jun, p-c-Jun, NF-κB, p-Akt, caused PC-3 cell death via caspase-dependent intrinsic signaling cascade ( Ahmad et al, 2020 ). Wogonoside inhibited PC-3 cell viability, migration, and invasion by suppressing Wnt/ β -catenin pathway and reversing EMT ( Wei et al, 2019 ).…”
Section: Experimental Researchmentioning
confidence: 99%