“…Brucine inhibited the expression of HSP70 and promoted the apoptosis of PC-3 cells ( Yan et al, 2022 ). Artemisinin inhibited c-Jun, p-c-Jun, NF-κB, p-Akt, caused PC-3 cell death via caspase-dependent intrinsic signaling cascade ( Ahmad et al, 2020 ). Wogonoside inhibited PC-3 cell viability, migration, and invasion by suppressing Wnt/ β -catenin pathway and reversing EMT ( Wei et al, 2019 ).…”