1984
DOI: 10.1016/0300-483x(84)90056-8
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Inhibition of the uptake of nucleoside in cultured harding-passey melanoma cells by diflubenzuron

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Cited by 15 publications
(6 citation statements)
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“…5). The high affinity of DFB supports the suggestion that DFB interferes with membrane processes and that the primary site of action will be found here and not in the inhibition of the chitin synthesis itself [8,11,12].…”
Section: Further Characterization Of Dfb-treated Cellssupporting
confidence: 86%
“…5). The high affinity of DFB supports the suggestion that DFB interferes with membrane processes and that the primary site of action will be found here and not in the inhibition of the chitin synthesis itself [8,11,12].…”
Section: Further Characterization Of Dfb-treated Cellssupporting
confidence: 86%
“…The exact biochemical lesion inflicted by these inhibitors is not known. Among the suggestions forwarded were 1) enhanced activities of phenoloxidase and chitinase [66]; 2) inhibition of proteases which convert the inactive zymogenic chitin synthase into an active enzyme [67]; 3) inhibition of DNA synthesis [68]; 4) inhibition of influx of nucleosides [69]; 5) interference with the insect hormonal balance [70]; and 6) inhibition of the speculative GlcNAc transporter [64]. Some of the suggested mechanisms of action such as 1, 3, and 4 have been regarded as secondary effects [3].…”
Section: Chitin From Polymer To Microfibrilmentioning
confidence: 99%
“…Among the chitin synthesis inhibitors, BPUs (or acylureas) are gaining importance in insect pest control because their effects can easily be monitored with chemical analyses and anti-tumour activity in animal tests (Mayer et al, 1984). Moreover, they are relatively harmless to natural enemies (Furlong et al, 1994).…”
Section: Introductionmentioning
confidence: 99%