Inhibition of α-glucosidase activity and intestinal glucose transport to assess the <i>in vivo</i> anti-hyperglycemic potential of dodecyl-acylated phlorizin and polydatin derivatives

Xu, Zhengming; Hileuskaya, Kseniya; Kraskouski, Aliaksandr; Yang, Yujiao; Huang, Zhe; Zhao, Zhengang

doi:10.1039/d3fo05233h

Cited by 3 publications

(1 citation statement)

References 61 publications

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“…f. (Chinese star anise) from a very long time used as a Chinese medicine and in the food industry [10] It is also used as a pain killer for relieving pain. essential oil extracted from Illicium verum containing anethole, used for flavoring drinks and confectionery [11]. Substances which neutralize free radicals contain antioxidant property.…”

Section: Introductionmentioning

confidence: 99%

Preliminary Phytochemical Analysis and Anti-Cholesterol Potential of Ethanolic Seed Extract of Illicium Verum

Vishnu Priya

et al. 2024

TIJPH

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Illicium Verum commonly called star anise, which is indigenous to northeast Vietnam and Southwest China. Illicium verum is one of the vital ingredients of Chinese medicinal herbs. Principal component (Trans-anethol) exhibits antimicrobial activity such as antiviral, anti-bacterial, antifungal and antiparasitic activities. Cholesterol, a waxy or fat like substance which is found in each and every cell of our body. Cholesterol helps our metabolism work efficiently, but if our body has too much cholesterol in blood, it causes several harmful effects. Anti-cholesterol drugs are useful in reducing the blood cholesterol level. Ethanolic extract of Illicium verum was found to be rich in phytochemicals such as Alkaloids, terpenoids and steroids. The ethanolic extract of illicium verum exhibited a significant antioxidant potential (Ic50 = 300 µg/ml) and anti-cholesterol potential (Ic50 = 400 µg/ml) as compared to standard drugs.

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Section: Introductionmentioning

confidence: 99%

Preliminary Phytochemical Analysis and Anti-Cholesterol Potential of Ethanolic Seed Extract of Illicium Verum

Vishnu Priya

et al. 2024

TIJPH

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Inhibitory mechanism of α-glucosidase by liquiritigenin and its combined effect with acarbose: Multi-spectroscopic analyses and molecular docking simulation

Zhou,

Wei,

Liao

et al. 2025

Food Bioscience

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Targeted and non-targeted metabolic characteristics of 6,7-dihydroxy-2,4- dimethoxyphenanthrene during simulated gastrointestinal digestion

Li,

Liu,

Liao

et al. 2025

Food Chemistry

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Inhibition of α-glucosidase activity and intestinal glucose transport to assess the in vivo anti-hyperglycemic potential of dodecyl-acylated phlorizin and polydatin derivatives

Abstract: A diet containing natural active compounds that can inhibit the hydrolytic activity of α-glucosidase on carbohydrates and intestinal glucose absorption is an effective means of controlling postprandial hyperglycemia. Phlorizin and...

Cited by 3 publications

References 61 publications

Preliminary Phytochemical Analysis and Anti-Cholesterol Potential of Ethanolic Seed Extract of Illicium Verum

Preliminary Phytochemical Analysis and Anti-Cholesterol Potential of Ethanolic Seed Extract of Illicium Verum

Inhibitory mechanism of α-glucosidase by liquiritigenin and its combined effect with acarbose: Multi-spectroscopic analyses and molecular docking simulation

Targeted and non-targeted metabolic characteristics of 6,7-dihydroxy-2,4- dimethoxyphenanthrene during simulated gastrointestinal digestion

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