Inhibitory Activity of Intracellular Lipid Accumulation by Various Marine Extracts in HepG2 Cells

Kim, Byoung-Mok; Jung, Ji-Hee; Kim, Dong-Soo; Kim, Young-Myoung; Jeong, In-Hak

doi:10.9721/kjfst.2012.44.3.362

Cited by 4 publications

(2 citation statements)

References 8 publications

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“…Furthermore, H. dybowskii is not exploited as a fisheries resource, but A. japonicus, which can easily be found in local fish markets in Korea, is commonly consumed in Gangwan-do. Therefore, the samples used in several studies (Kim et al 2008a;Lee et al 2011;Kim et al 2012), which were collected from fish markets, are more likely to be A. japonicus than H. dybowskii. Pectoral fin rays 9 9-10 13-16…”

Section: Discussionmentioning

confidence: 99%

“…In Korean, A. japonicus is called "Kka-na-ri"; however, Korean people who are not ichthyologists called this species "Yang-mi-ri" rather than "Kka-na-ri". Subsequently, some researchers have used the incorrect scientific name or the Korean common name (Kim et al 2008a;Lee et al 2011;Kim et al 2012). Providing wrong information can cause serious problems in communication and scholarship, so a correction is required.…”

Section: Introductionmentioning

confidence: 99%

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Redescription of the Korean sandlance Hypoptychus dybowskii from Korea

Kwun

Yim

2018

Fish Aquatic Sci

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Hypoptychus dybowskii, the Korean sandlance, is widespread in cold areas of the North Pacific. Although H. dybowskii has been considered to occur on the coast of Hamgyeongnam-do in Korea, the species is also distributed along the coast of Goseong-gun, Gangwon-do, south of Hamgyeongnam-do in the eastern part of the Korean Peninsula on the basis of newly collected specimens. In addition, many Koreans confuse H. dybowskii and Ammodytes japonicus (= A. personatus for Korean specimens) because the Korean common name or dialect of both species is "Yang-mi-ri", yet the two species differ in their external morphology. Hypoptychus dybowskii differs from A. japonicus in the location of the origin of the dorsal fin and the number of dorsal and anal fin rays.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Redescription of the Korean sandlance Hypoptychus dybowskii from Korea

Kwun

Yim

2018

Fish Aquatic Sci

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Inhibition of gene associated with Dyslipidemia and Antioxidative Effect of , and (ACR) on HepG2 cell model

et al. 2017

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Objectives: We performed this study to evaluate the antioxidative and hypolipidemic effect of Artemisia iwayomogi (韓茵蔯), Curcuma longa L. (鬱金) and Raphanus sativus L. (蘿葍子) (ACR). Method: We enriched Artemisiae Capillaris, Curcumae Longae and Raphani Semen compound with alcohol. ACR extract is treated to HepG2 cell. Cell groups are devided into 3 groups: normal, control and ACR treated group. We measured polyphenol, flavonoids, DPPH and ABTS radical scavenging activity, ROS, glutathione, GSH peroxidase, GSH reductase, SOD, catalase, free fatty acid, lipid peroxidation and suppression of ACAT1 and HMG-CoA reductase expression on mRNA level. Results: 1. ACR contained polyphenol and flavonoids and increased GSH significantly in HepG2 cell. 2. ACR increased GPx, GR, and catalase activity significantly in HepG2 cell. 3. ACR increased DPPH and ABTS radical scavenging activity significantly in HepG2 cell and decreased ROS. 4. ACR decreased free fatty acid and MDA significantly in HepG2 cell. 5. ACR suppressed ACAT1 and HMG-CoA reductase expression on mRNA level in HepG2 cell. Conclusion: This study suggests that ACR has antioxidative and hypolipidemic effect and might be effective in prevention and treatment of dyslipidemia.

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The Effects of Artemisiae Iwayomogii Herba, Curcumae Radix, and Aurantii Fructus Immaturus Complex Extract (ACA) on Dyslipidemia-related Factor Expression and Anti-oxidation in HepG2 Cells

Ryu¹,

Cho²,

Yoo³

et al. 2017

J Int Korean Med

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Objective&Methods The purpose of this study is to observe the effects of HK-1000 Herbal-acupuncture solution at GB34 (Yangleungchean) on hyperlipidemia and arteriosclerosis in rats. The author performed several experimental items to analyze the levels of various components and enzymes in serum, urine and liver, as well as the histological change of liver and aorta. Results1. HK-1000 herbal-acupuncture infusion increased the cell viability rate, DPPH radical scavenging activity and HMG-CoA reductase inhibition rate in rat liver cells.2. The levels of total cholesterol, free cholesterol, LDL-cholesterol, phospholipid in serum and AI (atherogenic index) were decreased, and the ratio of HDL to TCL(HDL/ TCL) and the level of TG in serum were increased as compared with those of the control group.3. In the HK-1000 group, serum AST and ALT were significantly lower than those of the HG group and saline group.4. Hepatic GSH and catalase activities were significantly increased as compared with those of the saline group. ConclusionsFrom the above results, it is suggested that HK-1000 herbal-acupuncture at GB34 has a therapeutic effect on hyperlipidemia and arteriosclerosis.

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Inhibitory Activity of Intracellular Lipid Accumulation by Various Marine Extracts in HepG2 Cells

Cited by 4 publications

References 8 publications

Redescription of the Korean sandlance Hypoptychus dybowskii from Korea

Redescription of the Korean sandlance Hypoptychus dybowskii from Korea

Inhibition of gene associated with Dyslipidemia and Antioxidative Effect of , and (ACR) on HepG2 cell model

The Effects of Artemisiae Iwayomogii Herba, Curcumae Radix, and Aurantii Fructus Immaturus Complex Extract (ACA) on Dyslipidemia-related Factor Expression and Anti-oxidation in HepG2 Cells

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