Inhibitory effect and possible mechanism of phenyllactic acid on <i>Aspergillus flavus</i> spore germination

Li, Minghua; Yao, Binbin; Meng, Xiumei

doi:10.1002/jobm.202200274

Cited by 14 publications

(8 citation statements)

References 38 publications

(63 reference statements)

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“…aureus . These findings are also consistent with Li et al. (2022) work, implying that the response of this compound to BC contributed to the suppression of disease-causing bacteria.…”

Section: Discussionsupporting

confidence: 90%

Plant growth and stress-regulating metabolite response to biochar utilization boost crop traits and soil health

Fallah,

Pang,

Lin

et al. 2023

Front. Plant Sci.

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IntroductionThe utilization of biochar (BC) as a soil amendment in agriculture has gained significant traction among many farmers and researchers, primarily due to its eco-friendly role in boosting crop output. However, the performance of specific metabolites (e.g., zeatin, melatonin, sucrose, and phenyllactic acid) in the various tissues of sugarcane plant (leaf, stem, and root) and rhizosphere soil-deemed plant growth and stress regulators in a long-term BC-amended field remains poorly understood. Additionally, literature on the shift in soil attributes and crop growth triggered by the strong response of these bioactive compounds to longterm BC utilization remains undocumented.MethodsMetabolome integrated with highthroughput sequencing analyses were conducted to identify and quantify the performance of plant growth and stress-regulating metabolites in a long-term BC-amended field. Additionally, we investigated how the response of these compounds to BC-treated soil influences crop traits and soil biochemical properties.ResultsWe also identified and quantified the performance of pathogenic bacteria and unraveled the association between these compounds and potential plant growth-promoting bacteria. The BC-supplemented soil significantly boosted the crop traits, including brix, sucrose content, and chlorophyll, as well as soil nutrients, such as soil total nitrogen (TN), ammonium (NH4+-N), and nitrate (NO3--N). We also noticed that metabolite-deemed plant growth and stress regulators, including melatonin and phenyllactic acid, were enriched considerably in the stem and root tissues of the BC-amended soil. Zeatin in the leaf, stem, and root tissues exhibited the same trend, followed by sucrose in the leaf tissue of the BC-treated soil, implying that the strong response of these compounds to BC utilization contributed to the promotion of crop traits and soil quality. Pathogenic bacteria belonging to Proteobacteria and Acidobacteria were suppressed under the BC-supplemented soil, especially in the root tissue and rhizosphere soil, whereas plant growth-regulating bacteria, mainly Bradyrhizobium, responded strongly and positively to several metabolites.DiscussionOur finding provides valuable information for agronomists, farmers, and environmentalists to make informed decisions about crop production, land use, and soil management practices. Proper soil assessment and understanding of the interaction between the attributes of soil, BC, and metabolites are essential for promoting sustainable agriculture practices and land conservation.

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“…aureus . These findings are also consistent with Li et al. (2022) work, implying that the response of this compound to BC contributed to the suppression of disease-causing bacteria.…”

Section: Discussionsupporting

confidence: 90%

Plant growth and stress-regulating metabolite response to biochar utilization boost crop traits and soil health

Fallah,

Pang,

Lin

et al. 2023

Front. Plant Sci.

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“…The energy supply of the PDA in the postinfection period is limited, resulting in a decrease in protein content, whereas the grain with rich nutrition can guarantee the energy supply for 7 days. Figure 3b shows that the ATP concentration of A. flavus on the grain was higher than the concentration on PDA ( p < .05), indicating that A. flavus on grain produced more energy, and the enzymes in A. flavus were in a highly utilized state (Li et al., 2022).…”

Section: Resultsmentioning

confidence: 99%

“…The experiment was performed according to the instruction manual. The absorbance of all samples was obtained at 660 nm by a UV/VIS spectrophotometer (Hu et al., 2020; Li et al., 2022; Zhang et al., 2023).…”

Section: Methodsmentioning

confidence: 99%

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Transcriptomics and metabolomic profiling identify molecular mechanism for Aspergillus flavus infection in grain

Ding,

Tian,

Liu

et al. 2023

Food Frontiers

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Aspergillus flavus is a ubiquitous saprophyte and opportunistic fungal pathogen with worldwide distribution, which causes diseases commonly in agricultural commodities and seriously threatens food security and human health. In this study, we try to reveal the mechanisms of A. flavus infection in grain from the perspective of apparent changes in physicochemical properties, microscopic structure, and ultrastructural changes at transcriptome–metabolomics levels. The results showed that the A. flavus infection included the preinfection (1–3 days) and postinfection period (4–7 days). The downregulated expression of creA promoted the cellulase expression and initiated infection. The metabolite oleic acid promoted infection as a nutrient carbon source and energy source. Then the entry of acetate units into the aflatoxin synthesis pathway was inhibited, whereas aflH, hypD, and hypB were significantly upregulated (p < .05) to stimulate the aflatoxin synthesis to complete the infection on the surface. During the postinfection period, the upregulation of aflS and other toxin‐producing regulatory genes accelerated aflatoxin synthesis and completed the internal infection. At the same time, the upregulation of vitamin B6 and allysine involved in amino acid metabolism, and galactose 1‐phosphate involved in energy metabolism ensured the production of acetyl‐CoA and the energy supply for A. flavus infection. The research findings highlight the underlying mechanisms of A. flavus infection at the transcriptome–metabolomics levels, which is important for developing effective strategies to prevent postharvest contamination.

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“…In particular, as an alternative to antibiotics, these LAB hold great promise for preventing mildew of silage. The inhibition activity of 3‐phenyllactic acid was related to its capacity to harm cell membranes and disrupt energy metabolism, which led to intracellular component leakage and decreased ATP synthesis, which in turn severely inhibited spore growth and even caused cell death (Li, Yao, & Meng, 2022 ). In addition, scanning electron microscope studies showed that the bacteria exposed to 3‐phenyllactic acid had damaged, even broken cell wall structure (Mu et al, 2012 ).…”

Section: Roles Of Functional Lab In Silage Prepara...mentioning

confidence: 99%

Current approaches on the roles of lactic acid bacteria in crop silage

Guo

et al. 2022

Microbial Biotechnology

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Lactic acid bacteria (LAB) play pivotal roles in the preservation and fermentation of forage crops in spontaneous or inoculated silages. Highlights of silage LAB over the past decades include the discovery of the roles of LAB in silage bacterial communities and metabolism and the exploration of functional properties. The present article reviews published literature on the effects of LAB on the succession, structure, and functions of silage microbial communities involved in fermentation. Furthermore, the utility of functional LAB in silage preparation including feruloyl esterase‐producing LAB, antimicrobial LAB, lactic acid bacteria with high antioxidant potential, pesticide‐degrading LAB, lactic acid bacteria producing 1,2‐propanediol, and low‐temperature‐tolerant LAB have been described. Compared with conventional LAB, functional LAB produce different effects; specifically, they positively affect animal performance, health, and product quality, among others. In addition, the metabolic profiles of ensiled forages show that plentiful probiotic metabolites with but not limited to antimicrobial, antioxidant, aromatic, and anti‐inflammatory properties are observed in silage. Collectively, the current knowledge on the roles of LAB in crop silage indicates there are great opportunities to develop silage not only as a fermented feed but also as a vehicle of delivery of probiotic substances for animal health and welfare in the future.

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Inhibitory effect and possible mechanism of phenyllactic acid on Aspergillus flavus spore germination

Cited by 14 publications

References 38 publications

Plant growth and stress-regulating metabolite response to biochar utilization boost crop traits and soil health

Plant growth and stress-regulating metabolite response to biochar utilization boost crop traits and soil health

Transcriptomics and metabolomic profiling identify molecular mechanism for Aspergillus flavus infection in grain

Current approaches on the roles of lactic acid bacteria in crop silage

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