1961
DOI: 10.1016/0042-6822(61)90149-0
|View full text |Cite
|
Sign up to set email alerts
|

Inhibitory effect of glutamine and ammonia on replication of influenza virus in ascites tumor cells

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
2
1

Citation Types

3
11
0

Year Published

1963
1963
2010
2010

Publication Types

Select...
6
3

Relationship

0
9

Authors

Journals

citations
Cited by 36 publications
(14 citation statements)
references
References 5 publications
3
11
0
Order By: Relevance
“…Higo, Kaneko, Kobayashi, Nakajima and Sasaki (4) described the effect of ammonium salts on influenza virus in suspended chorioallantoic membrane cultures. Although viral inhibition was measured only by hemagglutination titratiops, the results obtained were very similar to ours, and those of Eaton (2). In view of these observations, it was of interest to determine whether or not organic derivatives of ammonia, ix., the lower aliphatic amines, might possess a similar activity.…”
supporting
confidence: 64%
See 1 more Smart Citation
“…Higo, Kaneko, Kobayashi, Nakajima and Sasaki (4) described the effect of ammonium salts on influenza virus in suspended chorioallantoic membrane cultures. Although viral inhibition was measured only by hemagglutination titratiops, the results obtained were very similar to ours, and those of Eaton (2). In view of these observations, it was of interest to determine whether or not organic derivatives of ammonia, ix., the lower aliphatic amines, might possess a similar activity.…”
supporting
confidence: 64%
“…Ammonium ions in very low concentrations have been shown to inhibit completely the cytopathic effect (CPE) of influenza virus in tissue culture ( 1,2). This inhibition was accompanied by a very marked suppression of viral replication as measured by both infectivity and hemagglutination titrations.…”
mentioning
confidence: 98%
“…The effect of ammonium ions on influenza virus infection was described independently by Jensen et al (1961) and Eaton & Scala (1961), and was later extended to a large number of aliphatic amines (Jensen & Liu, 1963;Fletcher et al, 1965). The inhibitory effect of chloroquine has been reported with myxoviruses (Inglot, 1969;Schimizu et al, 1972;Matlin et al, 1981), rhabdoviruses (Schimizu et al, 1972;, retroviruses (Pazmino et al, 1974), togaviruses (Inglot, 1969, Helenius et al, 1980aTalbot & Vance, 1980), paramyxoviruses (Inglot, 1969;Schimizu et al, 1972;Durand et al, 1970), herpes viruses (Lancz et al, 1971;Banfield & Kirsch, 1973) and mouse hepatitis virus (Malucci, 1966).…”
Section: Discussionmentioning
confidence: 99%
“…Both the growth rate and the productivity of mammalian cells used for the production of biopharmaceuticals have been reduced under high ammonium concentration (Jensen and Liu, 1961;Ito and McLimans, 1981;Butler and Spier, 1984;Backer et al, 1988). In addition, the perturbation of protein glycosylation or secretion has been generated (Eaton and Scala, 1961;Throrens and Vasalli, 1986;Dyken and Sambanis, 1994;Jenkins and Curling, 1994). These examples include the inhibition of N-linked glycosylation of the recombinant protein mouse placental lactogen-I expressed in Chinese hamster ovary (CHO) cells by increasing levels of ammonium chloride (3 and 9 mM) (Borys et al, 1994); the reduction of final glycosylation reaction in the production of granulocyte colonystimulating factor by CHO cells (Anderson and Goochee, 1995); and the reduction of specific productivity of erythropoietin by inhibiting terminal sialylation (Chang et al, 1998).…”
Section: Introductionmentioning
confidence: 98%