Inhibitory Effect of Hydrogen Peroxide (H2O2) and Ionic Silver (Sanosil-25®) on Growth of a Pathogenic Bacterium (Vibrio harveyi) Isolated From Shrimp (Litopenaeus vannamei)

Abstract

Vibrio harveyi is a bacteria. It is a pathogen of shrimp which can cause vibriosis. It cause serious disease in the shrimp post larvae and defect in post larvae production. The aim of this study was to determine the concentration of Sanosil-25® which able to inhibit the bacterium growth. Therefore, Minimal Inhibitory Concentration (MIC) and Minimal Bactericidal Concentration (MBC) of sanosil-25 against Vibrio harveyi was determined by tube dilution method which recommended by National Committee for Clinical Laboratory Standards (NCCLS) in the laboratory condition. The results showed that MIC was 15 Part Per Million (ppm) and MBC was 20ppm during 48 hours. It showed that Sanosil-25 is an active antimicrobial agent against vibrio harveyi and can eradicate the bacteria from the water at concentration as well as 20ppm. Therefore, Sanosil-25 may be a useful chemical and for hygienic procedures of water against the bacterium. It didn't determined side effects of 20ppm of Sanosil-25 in shrimp.

In Vitro Control of Multidrug-Resistant Klebsiella pneumoniae Infection by Some Biocides used in Erbil Hospitals

“…without side effects. The two main components are hydrogen peroxide (H 2 O 2 ) as the oxidizing agent and silver (Ag+) (Ganjoor and Mehrabi, 2017). The sterilization mechanism of hydrogen peroxide depends on the release of oxygen free radicals, which causes genetic material damage (Totaro et al, 2020), proteins and lipids cleavage and cell death (Lin et al, 2020) in bacterium cells.…”