Inhibitory effect of Taemyeongcheong on allergic reactions

Abstract

Taemyeongcheong (TMC) is Korean traditional extracted drink with various health ingredients. TMC has been used to treat hepatic damage, obesity, gastritis, and colitis. However, the role of TMC on allergic reaction has not been studied yet. In this study, we investigated the anti-allergic effects of TMC against a compound 48/80-induced systemic anaphylactic reaction and IgE-mediated passive cutaneous anaphylaxis (PCA). TMC significantly inhibited the compound 48/80-induced systemic anaphylactic reaction and IgE-mediated PCA reaction. Furthermore, TMC reduced the levels of interleukin (IL)-1β, IL-4, IL-13, and vascular endothelial growth factor in the serum of mice under PCA reaction. Taken together, these results suggest that TMC can play a useful role as an anti-allergic agent.

<em>Ex Vivo Rumex Crispus</em> and <em>Cordyceps Sinensis</em> Mixture Regulates Immune Cells Responses to Pro-inflammatory Cytokines inC57BL/6 mice Splenocytes

“…Taemyeongcheong (TMC) is a health functional beverage made using traditional methods in Korea, and it is commonly found in various foods and herbal ingredients. TMC inhibits the allergic effects induced by 48/80 [21] and acetaminophen-induced hepatic damage in vivo [22]. We already reported that TMC inhibited Th2 cytokines such as IL-1β, IL-6, and IL-10 as well as iNOS and COX-2 in LPS-induced RAW 264.7 cells [23].…”

Rumex crispus and Cordyceps militaris Mixture Ameliorates Production of Pro-Inflammatory Cytokines Induced by Lipopolysaccharide in C57BL/6 Mice Splenocytes

“…Taemyeongcheong (TMC) is a health functional beverage made using traditional methods in Korea, and is commonly found in various foods and herbal ingredients. TMC inhibits the allergic effects induced by 48/80 (22) and acetaminophen-induced hepatic damage in vivo (23). We have previously reported that TMC inhibited Th2 cytokines such as IL-1β, IL-6, and IL-10 as well as iNOS and COX-2 in LPS-induced RAW 264.7 cells (24).…”