Inhibitory effects of Duchesnea chrysantha extract on ovalbumin-induced lung inflammation in a mouse model of asthma

Yang, Eun Ju; Lee, Ji-Sook; Yun, Chi‐Young; Kim, Joohwan; Kim, Jinsook; Kim, Dong‐Hee; Kim, In Sik

doi:10.1016/j.jep.2008.03.012

Cited by 39 publications

(28 citation statements)

References 27 publications

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“…Monocytes produce inflammatory cytokines and differentiate into inflammatory dendritic epidermal cells that induce the switch from Th2 to Th1/0 [29]. In the present study, …”

Section: Cytotoxic Effects On Hacat Cells In Vitromentioning

confidence: 60%

The Anti-Inflammatory Effects ofPicea wilsoniiMast on HaCaT Cells

Cha

2016

Korean J Clin Lab Sci.

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HaCaT 세포주에서 Picea wilsonii Mast의 항염효과 차경재 서해대학교 임상병리과Atopic dermatitis refers to a chronic, recurrent, skin condition, typically typified by itching, inflamed skin. It precedes other allergic diseases, such as asthma, food allergies, and allergic rhinitis, and is usually accompanied by various other immune disorders and secondary symptoms. In this study, we discovered that when treating TNF- and IFN--stimulated HaCaT cells with various concentrations of Picea wilsonii Mast (PwM) extracts, the cell viability was excellent. In addition, we measured the inflammatory cytokines associated with atopic dermatitis, including IL-6, IL-8, IL-13, and MCP-1. The production of IL-6, IL-13, and MCP-1 decreased in the presence of PwM extracts, whereas there was no significant difference in the production of IL-8. Further studies are necessary to develop an effective cure for atopic dermatitis and inflammation using foreign plant extracts, and PwM efficacy should be determined with an in-depth, objective verification process using protein and mechanism analysis.

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“…Monocytes produce inflammatory cytokines and differentiate into inflammatory dendritic epidermal cells that induce the switch from Th2 to Th1/0 [29]. In the present study, …”

Section: Cytotoxic Effects On Hacat Cells In Vitromentioning

confidence: 60%

The Anti-Inflammatory Effects ofPicea wilsoniiMast on HaCaT Cells

Cha

2016

Korean J Clin Lab Sci.

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“…13,19,20) However, the effects of Inulae flos have not previously been elucidated in an asthma model. We have demonstrated for the first time in this study that IFE inhibited the OVA-induced airway inflammation, and that this probably occurred due to decreases in leukocyte infiltration, AHR, Th2 cytokines and IgE production, as well as to mucus secretion in a mouse model of asthma.…”

Section: Discussionmentioning

confidence: 99%

Alleviation of OVA-Induced Airway Inflammation by Flowers ofInula japonicain a Murine Model of Asthma

Park

Lee

Choi³

et al. 2011

Bioscience, Biotechnology, and Biochemistry

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“…The medicine from crud drug has fewer side effects and more efficacy with or without current medicines. Although Chinese herbal medicines have uncertain values in therapies, a number of studies were reported that the effect of herbal medicines in asthma model (Yim et al, in press;Yang et al, 2008;Babayigit et al, 2009).…”

Section: Discussionmentioning

confidence: 99%