Inhibitory effects of molasses on mutation and nitric oxide production

Wang, Bor-Sen; Chang, Lee-Wen; Kang, Zhi-Chyang; Chu, Heuy-Ling; Tai, Huo-Mu; Huang, Ming‐Hsing

doi:10.1016/j.foodchem.2010.11.139

Cited by 24 publications

(17 citation statements)

References 27 publications

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“…After 1 h incubation, the reaction was terminated and the plates were incubated for 30 min, the formazan dye was dissolved by the dimethyl sulfoxide. The absorbance of each well was measured at 570 nm [13].…”

Section: Determination Of No Production In Raw 2647 Cellsmentioning

confidence: 99%

“…The mutagenic activity of WLL was evaluated by the Ames test with a 20 min first incubation at 37 °C [13]. The histidine-requiring strains of Salmonella typhimurium TA 98 and TA 100 were obtained from Taiwan Agricultural Chemicals and Toxic Substances Research Institute (Taichung, Taiwan).…”

Section: Mutagenicity Assaymentioning

confidence: 99%

“…The antimutagenic activity of WLL was conducted by the Ames method except for the addition of mutagen before incubation. The concentrations of mutagens were tested as in a previous study [13]. The mutagens used were 4-NQO (0.5 µg/plate), a direct mutagen; 2-AA (2.5µg/plate), which required S9 mix for metabolic activation.…”

Section: Antimutagenic Activity Assaymentioning

confidence: 99%

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Inhibitory Effects of Water Extracts of Longan Leaves on Mutation and Tyrosinase

Wang¹,

Wu²,

Chang³

et al. 2020

JFNR

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The antityrosinase and antimutation effects of longan leaves and its bioactive compounds was investigated. The water extracts of longan leaves (WLL) inhibited the mutagenicity of 2-aminoanthracene, an indirect mutagen, and 4-nitroquinoline-N-oxide, a direct oxidative mutagen toward Salmonella typhimurium TA 98 and TA 100. WLL at 0-0.6 mg/ml displayed free radical scavenging activity, reducing power, chelating ability and protection against lipid oxidative damage. In addition, the inhibitory actions of WLL on tyrosinase activity and nitric oxide (NO) production in lipopolysaccharide (LPS) stimulated macrophages RAW 264.7 cell increased in concentration-dependent manner. According to HPLC-DAD analysis showed that epicatechin, ellagic acid and gallic acid, the major phenolic compounds, were present in WLL. The phenolic components may in part account for contributing the protective effects of WLL. On the basis of the results obtained, WLL can display biological functions and effectively protective against oxidation, mutation, tyrosinase, and inflammation.

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Section: Determination Of No Production In Raw 2647 Cellsmentioning

confidence: 99%

Section: Mutagenicity Assaymentioning

confidence: 99%

See 1 more Smart Citation

Inhibitory Effects of Water Extracts of Longan Leaves on Mutation and Tyrosinase

Wang¹,

Wu²,

Chang³

et al. 2020

JFNR

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“…Sugarcane juice contains sucrose (approximately 16%), amino acids, vitamins, polyphenols, flavone, Nick acid, riboflavin, potassium, calcium, phosphorus, iron, sugarcane wax, and other nutrients (Asikin et al, ). Medical research shows that the abundant polyphenols and flavone in sugarcane juice has stronger ability to antioxidant, resist mutation, anti‐inflammatory and tyrosine enzyme inhibition (Duarte‐Almeida, Salatino, Genovese, & Lajolo, ; Takara, Otsuka, Wada, Iwasaki, & Yamashita, ; Wang et al, ). Sugarcane is also used to treat several health issues such as sore throat, cold, jaundice, hemorrhage, dysuria, anuria, and other urinary diseases in China.…”

Section: Introductionmentioning

confidence: 99%

Research on sugarcane juice fermentation by Ganoderma lucidum and assay of antioxidant activity of exopolysaccharide

Wang¹,

Huang²,

Liu³

et al. 2018

J Food Process Preserv

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A protocol for processing of the Ganoderma lucidum fermentation was carried out using sugarcane juice at 28°C for 14 d. The nonlinearity logistic growth curve model of G. lucidum is successfully fitted and the ideal highest biomass is estimated to be 5.42 g/L. G. lucidum was found to have a significant decrease effect on the pH value and sugar in sugarcane juice. The lowest pH (3.87 ± 0.01) was found on the 3rd day during fermentation. To the contrary, the release of exopolysaccharides and protein content noticeable increased, and free amino acids greatly enriched after the fermentation. Antioxidant activity tests showed exopolysaccharides can remarkably scavenge hydroxyl radicals, superoxide anion free radicals and DPPH free radicals. The sugar content of sugarcane juice was reduced by the fermentation of G. lucidum, and the content of active ingredients, such as polysaccharide increased, so it could be used as a new source of healthy foods. Practical applications Sugarcane is a traditional cash crop, which plays a pivotal role in many countries. As is well‐known, sugarcane juice fermentation drinks are comparatively uncommon in the market. The application of sugarcane juice fermentation by Ganoderma lucidum could combine the nutrients and health benefits of both sugarcane juice and G. lucidum, which provide a new way for sugarcane juice products processing. Fermented sugarcane juices may be developed into functional drinks for specific people.

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“…Sugarcane molasses contain various phytochemicals possessing beneficial biofunctions such as antioxidant, antibacterial, antimutation, and tyrosinase inhibitory functions . The extracts of these sugarcane‐manufacturing industry by‐products have the ability to prevent oxidative damage to DNA .…”

Section: Introductionmentioning

confidence: 99%

DNA damage protection against free radicals of two antioxidant neolignan glucosides from sugarcane molasses

et al. 2015

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The isolated neolignan glucosides from sugarcane molasses are able to protect DNA from oxidative damage caused by free radicals. This is the first identification of these two compounds in sugarcane molasses. The sugarcane molasses can therefore be used as potential nutraceutical preventative agents, and the findings may foster the utilization of this by-product as a bioresource-based product. © 2015 Society of Chemical Industry.

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Inhibitory effects of molasses on mutation and nitric oxide production

Cited by 24 publications

References 27 publications

Inhibitory Effects of Water Extracts of Longan Leaves on Mutation and Tyrosinase

Inhibitory Effects of Water Extracts of Longan Leaves on Mutation and Tyrosinase

Research on sugarcane juice fermentation by Ganoderma lucidum and assay of antioxidant activity of exopolysaccharide

DNA damage protection against free radicals of two antioxidant neolignan glucosides from sugarcane molasses

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