Inhibitory Effects of Solvent Extracts from Seven Brown Algae on Mutagenicity and Growth of Human Cancer Cells

Choi, Hyung-Ju; Kil, Jeung-Ha; Bak, Soon‐Sun; Kong, Chang‐Suk; Park, Kun-Young; Seo, Youngwan; Lim, Sangwoo

doi:10.5352/jls.2006.16.7.1080

Cited by 3 publications

(1 citation statement)

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“…Still, the inflow of thallus causes environmental and economic problems, such as fouling fishing boat screws, impeding fishing and sailing, becoming trapped in and damaging aquaculture facilities, and causing odors due to stranding of thallus on shorelines ( Byeon et al, 2019 ; Kim et al, 2019 ). Previous studies have demonstrated the ability of SH in prevention of cardiovascular disease ( Cardoso et al, 2015 ), inhibition of atopy ( Kim et al, 2020 ), inhibition of adipocyte production ( Kwon et al, 2019 ), inhibition of cancer cell growth ( Choi et al, 2006 ), and anticoagulation ( Kim et al, 2004 ).…”

Section: Introductionmentioning

confidence: 99%

Effects of Sargassum horneri and Ulva australis Extracts on Body Weight and Serum Glucose Levels of Sprague-Dawley Rats

Lee

Yeo

Yoon

et al. 2021

Prev. Nutr. Food Sci.

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This study investigated the safety and functionality of a functional additive for humans and animals from Sargassum horneri (SH) and Ulva australis (UA) waste for recycling marine refuse generated in large quantities in Jeju. Sprague-Dawley rats were orally administered functional additives at 2,000 mg/kg to assess 14-day repeated dose toxicity of the two extracts. For female rats, weight gain after administration of SH was 66.2±18.8% vs. controls. Male rats administered UA showed weight gain of 92.3±8.0% vs. controls. SH and UA significantly decreased serum glucose levels in male rats compared with controls (79.8±11.10% and 76.1±9.67%, respectively). Similarly, significant decrease in serum glucose levels were shown for female rats after administration of SH and UA (79.2±1.58% and 82.8±3.21%, respectively). Furthermore, rats showed significant differences vs. controls in several serological parameters after receiving extracts, however results remained within the normal range. Thus, the SH and UA extracts were considered safe substances that may be used as functional additives to help reduce body weight and serum glucose.

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