Inhibitory effects of vitamin E on collagen synthesis and wound repair

Effects of nicotine in the presence and absence of vitamin E on morphology, viability and osteogenic gene expression in MG-63 osteoblast-like cells

“…Our findings were similar to those of previous studies, indicating that nicotine increased the number of vacuolated cells and significantly decreased the proliferation of cells at the final concentration of 5 mM, which equals the average concentration of nicotine in the saliva of smokers [31,32]. In addition, vitamin E as a lipophilic antioxidant is a lysosomal stabilizer [33] and improves the integrity of biologic membranes by preventing lipid peroxidation [34]. Moreover, vitamin E deactivates tissue degradation enzymes by its antioxidant properties, activates tissue degradation inhibitors [35] and consequently prevents cell lysis [36].…”

The impact of antioxidant agents complimentary to periodontal therapy on oxidative stress and periodontal outcomes: A systematic review

“…[65][66][67] This vitamin is essential for normal reproduction in humans, development of muscles and a variety of physiological and biochemical functions. In one of the selected studies, vitamin E was used complimentarily to SRP.…”

A Review of the Biologic Effects, Clinical Efficacy, and Safety of Silicone Elastomer Sheeting for Hypertrophic and Keloid Scar Treatment and Management

“…Even though Baumann and Spencer 86 reported no benefit in the cosmetic outcome of scars after topical application of vitamin E, vitamin E has been advocated as an anti-inflammatory agent capable of reducing the number of fibroblasts and retarding the accumulation of collagen. 87 A separate study found silicone gel sheets enhanced with vitamin E to be superior over silicone alone in the treatment of hypertrophic and keloid scars. 88 de Oliveira and colleagues 55 have found that the silicone component of scar dressings may not be necessary for efficacy in scar management.…”