Inhibitory effects of water extract from longan twigs on mutation and nitric oxide production

Wang, Bor-Sen; Tang, Chi-Hua; Chiu, Chih-Yi; Huang, Ming‐Hsing

doi:10.1016/j.foodchem.2012.04.125

Cited by 16 publications

(14 citation statements)

References 27 publications

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“…Ellagic acid also inhibited LPS-induced expression of enzymes involved in the synthesis of prostaglandin E2 in human monocytes [25]. Ellagic acid found in WLP also showed significant antioxidant effects by various antioxidation assays [26]. Thus, ellagic acid exhibited the high efficiency in WLP, which can benefit the pharmaceutical and food industry.…”

Section: Discussionmentioning

confidence: 99%

Antioxidant and Anti-Inflammatory Properties of Longan (Dimocarpus longanLour.) Pericarp

Huang

Wang

Lin

et al. 2012

Evidence-Based Complementary and Alternative Medicine

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This study examined the antioxidant and anti-inflammatory activities of the water extract of longan pericarp (WLP). The results showed that WLP exhibited radical scavenging, reducing activity and liposome protection activity. In addition, WLP also inhibited lipopolysaccharide (LPS)-induced nitric oxide (NO) production in macrophages. Further, administration of WLP, in the range of 100–400 mg/kg, showed a concentration-dependent inhibition on paw edema development following carrageenan (Carr) treatment in mice. The anti-inflammatory effects of WLP may be related to NO and tumor necrosis factor (TNF-α) suppression and associated with the increase in the activities of antioxidant enzymes, including catalase, superoxide dismutase, and glutathione peroxidase. Overall, the results showed that WLP might serve as a natural antioxidant and inflammatory inhibitor.

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Section: Discussionmentioning

confidence: 99%

Antioxidant and Anti-Inflammatory Properties of Longan (Dimocarpus longanLour.) Pericarp

Huang

Wang

Lin

et al. 2012

Evidence-Based Complementary and Alternative Medicine

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“…[22]. GA has been reported to have antibacterial [23,24], antifungal [25], antioxidant [26], anticancer [27], antiinflammatory [28], antiviral [29] and antimutation properties [30]. Although several studies have revealed that GA exerts antimicrobial effects toward human pathogens, few studies have reported on the antimicrobial action against aquatic pathogens.…”

Section: Mechanisms Of Action Of Asgc and Ga Against V Harveyimentioning

confidence: 99%

Extraction, identification and mechanism of action of antibacterial substances from Galla chinensis against Vibrio harveyi

Guo¹,

Wang²,

Feng³

et al. 2020

Biotechnology & Biotechnological Equipment

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The aim of this study was to investigate the extraction of antibacterial substances from Galla chinensis (ASGC) that act against the aquatic pathogen Vibrio harveyi, to identify the chemical composition and explore the mechanism of action. The optimal extraction process was as follows: anhydrous methanol, liquid/material ratio (mL/g) 26:1, extraction temperature 98 C and extraction time 157 min. The diameter of the inhibition zones (21.31 ± 0.51 mm) under the optimal conditions agreed with the predicted value by experimental rechecking. The yield of ASGC was 39.39% ± 0.69%, and two compounds including gallic acid (GA) and penta-O-galloyl-b-D-glucose (5GG) were identified in ASGC. The minimal inhibitory concentration (MIC) values of ASGC and GA were 0.50 and 0.25 mg/mL, respectively. Meanwhile, 5GG and other chemical constituents did not exert antibacterial activities against V. harveyi (MICs > 1 mg/mL). Further investigation of the mechanisms of action of ASGC and GA against V. harveyi revealed their strong destructive effects on the growth of bacterial cells, the integrity and permeability of the cell membrane, and morphological alterations. The report provides a favorable prospect of GA as a potential control agent against V. harveyi in aquaculture.

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“…Previous study has shown the anti-inflammatory effect of longan flower, twigs, and pericarp (Ho et al, 2007;Huang et al, 2012;Wang et al, 2012). On the other hand, fresh and dried longan aril extracts significantly increased basal prostaglandin E 2 (PGE 2 ) production and tended to elevate LPSstimulated PGE 2 production in RAW264.7 macrophages (Huang and Wu, 2002).…”

Section: Introductionmentioning

confidence: 97%

Longan ( Dimocarpus longan Lour.) inhibits lipopolysaccharide-stimulated nitric oxide production in macrophages by suppressing NF-κB and AP-1 signaling pathways

Kunworarath

Rangkadilok

Suriyo

et al. 2016

Journal of Ethnopharmacology

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Inhibitory effects of water extract from longan twigs on mutation and nitric oxide production

Cited by 16 publications

References 27 publications

Antioxidant and Anti-Inflammatory Properties of Longan (Dimocarpus longanLour.) Pericarp

Antioxidant and Anti-Inflammatory Properties of Longan (Dimocarpus longanLour.) Pericarp

Extraction, identification and mechanism of action of antibacterial substances from Galla chinensis against Vibrio harveyi

Longan ( Dimocarpus longan Lour.) inhibits lipopolysaccharide-stimulated nitric oxide production in macrophages by suppressing NF-κB and AP-1 signaling pathways

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