Initial analysis of archived non-human primate frontal and rear impact data from the biodynamics data resource

Olszko, Ardyn; Beltran, Christine M; Vasquez, Kimberly B; McGhee, James; Chancey, Valeta Carol; Yoganandan, Narayan; Pintar, Frank A.; Baisden, Jamie

doi:10.1080/15389588.2017.1390570

Cited by 7 publications

(2 citation statements)

References 24 publications

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“…The macaque is an animal of great experimental value because of its close resemblance to humans in terms of spinal anatomy and motor physiology and function [16] . Experimental and clinical operation studies in spinal surgery have higher requirements on the spinal anatomy, biomechanics, and the intervertebral disc's soft tissue structure [17][18] . Using animals with similar species to humans for comparative anatomical studies can further increase relevant animal experimental results and the reliability of animal models.…”

Section: Introductionmentioning

confidence: 99%

Finite element modeling and comparative mechanical analysis of cervical facet joints in humans and macaques

Zhao,

Lv,

Shi

et al. 2023

Preprint

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Purpose To establish a finite element model of the adult cervical spine and the adult macaque cervical spine and to compare the stress and displacement changes between the two under six working conditions through finite element analysis around the stress characteristics of the facet joint, to provide a theoretical basis for clinical vertebral body replacement. Methods One 40-year-old adult volunteer and one 7-year-old adult male macaque were selected and subjected to spiral CT thin-layer scans, respectively. Moreover, the original cervical spine CT data were imported into Mimics 21.0 to establish a three-dimensional model. The models of cervical spine segments, discs, and ligaments were optimized, assigned, and assembled to organize the mesh. Finally, using Abaqus, the cervical spine finite element model was loaded with 75 N additional load and 1 N-m external dip moment. To discover the mechanical trends and differences by conducting the automated comparison analysis under six working conditions of anterior flexion, posterior extension, left and right lateral flexion, and left and proper rotation. Results Both human and macaque cervical vertebrae have cervical facet joints. Furthermore, finite element modeling comparison revealed that the uncovertebral joints' stress and displacement changes were generally consistent between the two. The stress and displacement concentrations were all at C6. There was a significant difference between the human and the macaque. Conclusions Macaques can be the best alternative animal model for clinical studies of the cervical spine, providing a theoretical basis for clinical cervical vertebral body replacement and other aspects.

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Section: Introductionmentioning

confidence: 99%

Finite element modeling and comparative mechanical analysis of cervical facet joints in humans and macaques

Zhao,

Lv,

Shi

et al. 2023

Preprint

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show abstract

“…In addition, the neck musculature surrounding the spinal column enables the dynamic movement and stability of the head and neck. Yet the understanding of the muscle activation schemes in the context of spinal injury risk during motor vehicle accidents requires further development (Olszko et al, 2018). This is important information as approximately one-quarter of the four million emergency room visits per year from motor vehicle traffic injuries in the United States are associated with neck and back strains and sprains (Albert and McCaig, 2015).…”

Section: Introductionmentioning

confidence: 99%

Optimization of muscle activation schemes in a finite element neck model simulating volunteer frontal impact scenarios

Correia

McLachlin

Cronin

2020

Journal of Biomechanics

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Vestibulocollic and Cervicocollic Muscle Reflexes in a Finite Element Neck Model During Multidirectional Impacts

2021

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Active neck musculature plays an important role in the response of the head and neck during impact and can affect the risk of injury. Finite element Human Body Models (HBM) have been proposed with open and closed-loop controllers for activation of muscle forces; however, the controllers in many current models are often calibrated to specific experimental loading cases, without considering the intrinsic role of physiologic muscle reflex mechanisms under different loading conditions. The goal of this study was to develop a closed-loop controller for a contemporary male HBM to represent muscle activation mechanisms based on the vestibulocollic and cervicocollic reflexes. Dual PID controllers were implemented, with head rotation and muscle stretch used for input.Controller parameters were optimized using volunteer data and then independently assessed across twelve impact conditions. The kinematics from the closed-loop controller simulations showed good average correlations to the experimental data (0.699) for the impacts. Compared to a previous optimized open-loop activation strategy, the average difference was less than 9%. The incorporation of the reflex mechanisms using a closedloop controller can provide robust performance for a range of impact directions and severities, which is critical to improving HBM response under a larger spectrum of automotive impact simulations.

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Initial analysis of archived non-human primate frontal and rear impact data from the biodynamics data resource

Cited by 7 publications

References 24 publications

Finite element modeling and comparative mechanical analysis of cervical facet joints in humans and macaques

Finite element modeling and comparative mechanical analysis of cervical facet joints in humans and macaques

Optimization of muscle activation schemes in a finite element neck model simulating volunteer frontal impact scenarios

Vestibulocollic and Cervicocollic Muscle Reflexes in a Finite Element Neck Model During Multidirectional Impacts

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