Initial Clinical Evaluation of the NovaScan Carbon Dioxide Laser Handpiece

Rj, Koch

doi:10.1111/j.1524-4725.1998.tb04169.x

Cited by 4 publications

(4 citation statements)

References 3 publications

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“…In this study, eyes treated with the NovaScan had significantly greater corneal thickness and demonstrated greater endothelial cell loss. The NovaScan has a 3 mm ‘effective’ spot size according to laser engineers with a power density between 30 and 40 W/cm 2 16 . However, the rapid oscillation of the scanner and slow movement across the target tissue surface may lead to excessive overlap and increased tissue thermal injury, resulting in greater endothelial damage found in this study.…”

Section: Discussionmentioning

confidence: 83%

“…Unexpected results were obtained particularly for the NovaScan handpiece. The NovaScan CO 2 laser scanner converts to continuous wave or pulsed beam of laser energy into a scanned, shuttered beam to reduce tissue carbonization and enhance precision of vaporization 16 . The robotized scanner provides a nonaligned treatment pattern to decrease dwell time on the target to diminish thermal energy in adjacent tissue.…”

Section: Discussionmentioning

confidence: 99%

“…The NovaScan CO 2 laser scanner converts to continuous wave or pulsed beam of laser energy into a scanned, shuttered beam to reduce tissue carbonization and enhance precision of vaporization. 16 The robotized scanner provides a nonaligned treatment pattern to decrease dwell time on the target to diminish thermal energy in adjacent tissue. In this study, eyes treated with the NovaScan had significantly greater corneal thickness and demonstrated greater endothelial cell loss.…”

Section: Discussionmentioning

confidence: 99%

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Light and electron microscopic evaluation of canine corneal endothelium following CO₂ photokeratotomy

Hoffman

Ownby

Lehenbauer

et al. 2009

Veterinary Ophthalmology

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Objective To determine using light and scanning electron microscopy if treatment with CO 2 photokeratotomy alters the corneal endothelium in healthy dogs. Procedure Eight surgery laboratory dogs were determined to be free of ocular abnormalities. Under general anesthesia, the left eye of each dog was treated in a quadrant from 12 to 3 o'clock with the CO 2 laser in a defocused mode. The right eye served as a control. There were four treatment groups, each with 2 dogs: group 1 (2 W, 0.1 J/s, 0.8 mm tip), group 2 (3 W, 0.3 J/s, 0.8 mm tip), group 3 (2 W, 0.04 J/s NovaScan), group 4 (3 W, 0.06 J/s, NovaScan). The 0.8 mm tip delivered a power density of 382 W/cm 2 or 573 W/cm 2 , at 2 or 3 watts respectively. TheNovaScan handpiece delivered a power density of 30 W/cm 2 or 40 W/cm 2 , at 2 or 3 Watts respectively. Following euthanasia, right and left corneas including a 2-mm scleral rim were harvested and fixed in commercial grade Karnovsky's fixative. One piece of cornea was processed routinely, embedded in Embed 812 resin, sectioned at 1 um, stained with toluidine blue and evaluated with the light microscope. A separate piece of each cornea was routinely processed and examined with a JEOL 6400 scanning electron microscope (SEM) at 20 KV. Results No changes in endothelial cell morphology were detected by light microscopy in the sections examined. SEM indicated normal endothelial cell morphology in control eyes with presumed artifactual changes at the corneal free margin (4/8 eyes). Multiple punctate to linear regions of endothelial cell destruction were observed in 6/8 laser-treated corneas. A significant increase in corneal thickness ranging from 1.90 to 37.28% was observed in all laser treated corneas. This increase in thickness correlated linearly with the degree of endothelial damage. Ultrastructural findings also correlated with postoperative clinical findings. Conclusion CO 2 laser photokeratotomy alters corneal endothelial cell morphology and thickness.

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Section: Discussionmentioning

confidence: 83%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

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Light and electron microscopic evaluation of canine corneal endothelium following CO₂ photokeratotomy

Hoffman

Ownby

Lehenbauer

et al. 2009

Veterinary Ophthalmology

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“…The most dramatic improvement in elasticity and rhytid resolution was found in the CO 2 cohort. This effect was quantitatively measured at 6 months with a Cutometer, which found a mean increase in skin elasticity of 18.2% [27]. Visual assessment by the treating facial plastic surgeon (R.J.K.)…”

Section: Clinical Correlations: Observations In 100 Casesmentioning

confidence: 99%

In vivo model of histologic changes after treatment with the superpulsed CO2 laser, Erbium:YAG laser, and blended lasers: A 4- to 6-month prospective histologic and clinical study

Greene¹,

Egbert²,

Utley³

et al. 2000

Lasers Surg. Med.

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Collagenesis is greatest with CO(2) and least with Er:YAG. Elastosis decreased to the greatest degree with CO(2), least with erbium, and to an intermediate extent with blended CO(2)/Er:YAG regimens (sequential and Derma-K). These changes from control are statistically significant with all regimens (P < 0.05). Blended CO(2)/Er:YAG treatments provide an optimal combination of the benefits of CO(2) but with lesser erythema and healing delay. Clinical and histologic findings change over time for different treatments. Thus, long-term histology is critical for predicting results of treatment.

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Laser resurfacing for facial acne scars

Jordan

Cummins²,

Burls

et al. 2001

Cochrane Database of Systematic Reviews

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Initial Clinical Evaluation of the NovaScan Carbon Dioxide Laser Handpiece

Abstract: The NovaScan CO2 laser handpiece is a safe tool for skin resurfacing. In its initial use over a 6-month period there were no device-related complications.

Cited by 4 publications

References 3 publications

Light and electron microscopic evaluation of canine corneal endothelium following CO₂ photokeratotomy

Light and electron microscopic evaluation of canine corneal endothelium following CO₂ photokeratotomy

In vivo model of histologic changes after treatment with the superpulsed CO2 laser, Erbium:YAG laser, and blended lasers: A 4- to 6-month prospective histologic and clinical study

Laser resurfacing for facial acne scars

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Initial Clinical Evaluation of the NovaScan Carbon Dioxide Laser Handpiece

Abstract: The NovaScan CO2 laser handpiece is a safe tool for skin resurfacing. In its initial use over a 6-month period there were no device-related complications.

Cited by 4 publications

References 3 publications

Light and electron microscopic evaluation of canine corneal endothelium following CO2 photokeratotomy

Light and electron microscopic evaluation of canine corneal endothelium following CO2 photokeratotomy

In vivo model of histologic changes after treatment with the superpulsed CO2 laser, Erbium:YAG laser, and blended lasers: A 4- to 6-month prospective histologic and clinical study

Laser resurfacing for facial acne scars

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Product

Resources

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Light and electron microscopic evaluation of canine corneal endothelium following CO₂ photokeratotomy

Light and electron microscopic evaluation of canine corneal endothelium following CO₂ photokeratotomy