Initial description of pork-cat syndrome in the United States

Posthumus, Jonathon; James, Hayley R.; Lane, Charles J.; Matos, Luis A.; Platts-Mills, Thomas A.E.; Commins, Scott P.

doi:10.1016/j.jaci.2012.12.665

Cited by 75 publications

(62 citation statements)

References 6 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Class 2 food allergy is developed as a consequence of respiratory sensitization to inhalant allergens. Examples of class 2 food allergy include pollen-plant food allergies (Geroldinger-Simic et al 2011), bird-egg allergies (Quirce et al 2001), cat-pork allergies (Posthumus et al 2013), and mite-seafood allergies (Boquete et al 2011).…”

Section: Exposure To Food Allergens Sensitizationmentioning

confidence: 99%

Food Allergy

Sathe

Liu

Zaffran

2016

Annu. Rev. Food Sci. Technol.

View full text Add to dashboard Cite

Food allergy is receiving increased attention in recent years. Because there is currently no known cure for food allergy, avoiding the offending food is the best defense for sensitive individuals. Type I food allergy is mediated by food proteins, and thus, theoretically, any food protein is a potential allergen. Variability of an individual's immune system further complicates attempts to understand allergen-antibody interaction. In this article, we briefly review food allergy occurrence, prevalence, mechanisms, and detection. Efforts aimed at reducing/eliminating allergens through food processing are discussed. Future research needs are addressed.

show abstract

Section: Exposure To Food Allergens Sensitizationmentioning

confidence: 99%

Food Allergy

Sathe

Liu

Zaffran

2016

Annu. Rev. Food Sci. Technol.

View full text Add to dashboard Cite

show abstract

“…Similarly, the cat-pork syndrome is based on cross-reactivity between Fel d 2 and pork serum albumin (Sus s 6). In this rare syndrome, patients develop an IgE antibody response specific for cat serum albumin Fel d 2 that cross-reacts with porcine albumin Sus s 6 and can lead to severe or even fatal allergic reactions on occasions when pork is consumed [98]. …”

Section: Introductionmentioning

confidence: 99%

Indoor Allergens and Allergic Respiratory Disease

Pomés

Chapman

Wünschmann

2016

Curr Allergy Asthma Rep

View full text Add to dashboard Cite

Purpose of review The purpose of this review is to evaluate the most recent findings on indoor allergens and their impact on allergic diseases. Recent findings Indoor allergens are present inside buildings (home, work environment, school), and given the chronic nature of the exposures, indoor allergies tend to be associated with the development of asthma. The most common indoor allergens are derived from dust mites, cockroaches, mammals (including wild rodents and pets), and fungi. The advent of molecular biology and proteomics has led to the identification, cloning, and expression of new indoor allergens, which have facilitated research to elucidate their role in allergic diseases. This review is an update on new allergens and their molecular features, together with the most recent reports on their avoidance for allergy prevention and their use for diagnosis and treatment. Summary Research progress on indoor allergens will result in the development of new diagnostic tools and design of coherent strategies for immunotherapy.

show abstract

“…Given the short course of 30 minutes after consuming pork rinds, consideration for catepork syndrome could be entertained; however, if this were the case, then the IgE level to beef would likely be negative. 21 Catepork syndrome is with a different entity than alpha-gal, and reactions to pork are immediate, not delayed. In catepork syndrome, the IgE to alpha-gal is not the mediator; rather, the IgE is specific to cat serum albumin.…”

Section: Differential Diagnosismentioning

confidence: 99%

“…In catepork syndrome, the IgE to alpha-gal is not the mediator; rather, the IgE is specific to cat serum albumin. 17,21 Patients with catepork syndrome initially have sensitivity to cat albumin, and later in life the cross-reactivity leads to the pork allergy. 14 In the present patient, the normal tryptase level, elevated IgE level to alpha-gal and beef, and the time course from the ingestion of beef brisket indicate that the diagnosis is a red meat allergy owing to alpha-gal sensitization.…”

Section: Differential Diagnosismentioning

confidence: 99%