“…Irreversible immobilization of the antimicrobial agents in the device offers an alternative motif that eliminates patient exposure to elutable active agents and potentially increases the duration of antimicrobial efficacy. 8,9 A wide range of antimicrobial agents have been immobilized, including small molecules (e.g., quaternary ammonium silanes), [10][11][12][13][14][15][16][17] quaternary ammonium polymers, [18][19][20][21][22][23][24][25][26][27][28][29][30][31][32][33][34][35] polyamines, [36][37][38][39][40][41][42] chitosan, [43][44][45][46][47][48][49] enzymes, [50][51][52][53][54][55] peptides, and peptide mimetics. …”