Daniels[1] has raised a number of issues relevant to our 3-ounce water swallow challenge study [2] and specifically to silent aspiration risk is volume-dependent [3]. We welcome the opportunity to clarify the issues.We were not the first to report on the utility of the 3-ounce water swallow test [4]. We have, however, increased the population sample from the original 44 stroke patients to 3,000 participants with a wide variety of diagnoses found in the acute care setting, thereby fostering generalization and more widespread use. Further research incorporated a basic cognitive assessment [5] and oral mechanism evaluation resulting in a 3-ounce water swallow challenge protocol that has the additional advantages of reliably and safely identifying patients with aspiration risk and successfully recommending specific oral diets for different patient populations, i.e., trauma patients [6], general acute care inpatients [7], and patients with acute stroke [8]. The protocol's strengths include prospective, consecutive, and referral-based population samples that span the age range [9].We are grateful for this opportunity to clarify the misunderstanding that patients were excluded from the 3-ounce water swallow challenge due to safety issues [1]and we take umbrage at the suggestion that patients were excluded in the initial study [2] but not reported.All patients were tested with 3 ounces of water regardless of fiberoptic endoscopic evaluation of swallowing (FEES) results [2,3]. Only during FEES were 313 participants deemed unsafe to be given thin liquid and 110 participants were deemed unsafe to be given puree but all still participated in the 3-ounce water swallow challenge. The corrected wording is ''It was deemed unsafe to give 313 participants thin liquid consistency boluses based on FEES results but they all participated in the 3-ounce water swallow challenge.'' The same wording applies to the 110 participants not given puree consistency on FEES. Our study design and methodology remained the same [2,3,5,9], and the validity of the 3-ounce water swallow challenge protocol to both determine aspiration risk and make safe and successful diet recommendations has not been compromised [6][7][8].We are continuing our programmatic line of research in order to corroborate our results with blinded testing, correlating oral mechanism findings with aspiration risk, and collecting longitudinal data regarding success of diet recommendations all based on the 3-ounce water swallow challenge protocol. We are confident that our research and recommendations to improve patient care by fostering safer swallowing will stand the test of time.
References1. Daniels SK. Letter by Daniels regarding article ''Silent aspiration risk is volume-dependent''. Dysphagia. 2012;27. doi:10.1007/ s00455-011-9391-8. 2. Suiter DB, Leder SB. Clinical utility of the 3 ounce water swallow test. Dysphagia. 2008;23:244-50.