Injectable, adhesive, self-healing and conductive hydrogels based on MXene nanosheets for spinal cord injury repair

Photoactivated MXene Nanosheets for Integrated Bone–Soft Tissue Therapy: Effect and Potential Mechanism

“…Compared with previous studies on MXene for tissue repair, − our work presented several advantages. First, in this study, aiming at the complex environment of bone tissue with surrounding soft tissue damage, the repair of bone tissue and soft tissue is taken into account, which provides an effective strategy for the postoperative repair and treatment of clinical bone defects.…”

Highly adhesive chitosan/poly(vinyl alcohol) hydrogels via the synergy of phytic acid and boric acid and their application as highly sensitive and widely linear strain sensors

“…The interfacial adhesion of PA may be from the electrostatic interaction and hydrogen bonding between its phosphate groups and the substrates. 25 However, it should be noted that high concentrations of PA are required when using PA alone as the adhesive component. 24 Although BA alone did not provide sufficient interfacial adhesion, it was found to highly affect the adhesion strength of CS/PVA–PA–BA hydrogels.…”

“…24 Yu et al utilized PA as the adhesive compound to develop a novel polyvinylpyrrolidone/PA/MXenes hydrogel that had adhesion, injectability, self-healing property, and conductivity. 25 However, the adhesive strength of the reported hydrogels with PA is still not high enough to meet the practical requirement.…”

Injectable hydrogels in central nervous system: Unique and novel platforms for promoting extracellular matrix remodeling and tissue engineering

“…In conclusion, their data showed that the hydrogels had the potential to aid in the recovery of locomotor function in rats with SCI ( Fig. 10 ) [ 231 , 232 ]. In a work, scientists combine electroconductive and biocompatible ECM-based hydrogels to design spinal cord tissue engineering materials for traumatic SCI.…”