The study of inclusive science education poses researchers with new challenges and tasks. There is an inherent complexity within this field as it requires understanding of science subject matter in combination with the normative demands of inclusive pedagogy. A Delphi study was conducted to systematically survey research challenges that arise in the research of inclusive science education from the perspective of experts. In the Delphi study, challenges for research on inclusive science education were identified using an exploratory approach in the first round. In the course of the following rounds, a consensus could be reached for eight challenges (> 50% agreement, IQR < 1, SD < 1.5). These included challenges known from the literature, e.g. a lack of suitable research instruments. The results also showed a change or an overcoming of challenges documented in earlier articles. For example, many experts, no longer experience a lack of research studies as a challenge. Alongside the progress made in the research field of inclusive science education, challenges still need to be addressed, such as the discrepancy between existing theoretical approaches and actual teaching practices. Future research must address these issues.