Flow separation under crosswind conditions seriously jeopardizes the quality of the nacelle's ow eld. In this paper, microsecond pulsed surface dielectric barrier discharge (µSDBD) is used to suppress the ow separation and reduce the crosswind distortion of the nacelle. The ow structure induced by the µSDBD is rst explored by a high-speed schlieren system. The pressure waves composed of a cylindrical wave surrounding the electrodes and a at wave at the top of the cylindrical one can be perceived, which indicates the fast gas heating produced by the µSDBD. A set of wind tunnel tests are then conducted to verify the ability of µSDBD to suppress the nacelle ow separation and study the in uence laws of pulse frequency, coverage area, and the actuator layout on the ow control effects. Results show that plasma actuation can not only improve the total pressure at the exit of the nacelle but also suppress the ow distortion caused by the crosswind. The best ow control effect can be achieved at the pulse frequency of 500Hz, with the value of sectional distortion coe cient reduced by 57.76% compared with the baseline condition. The ow control effect with the plasma actuator covering 120° of the nacelle perimeter is better than that of 60° and 180° coverage, showing the highest ow control e ciency in the 120°c ondition. The µSDBD can improve mixing between the boundary layer and the main ow, enhancing the ability of the boundary layer to resist the adverse pressure gradient, which is bene cial to ow separation control.