Scientific review of the latest author’s works on tectonics and geodynamics of the territory of Ukraine, as well as its connection with the localization of mineral deposits, is presented. The structure and evolution of lithosphere of the Carpathian and Black Sea segments of Ukraine, the Dnieper-Donetsk Basin, Donbass Foldbelt and Ukrainian Shield has been reconstructed based on the interpretation of regional deep sounding (DSS) and reflection (CDP) seismic profiles, the geomagnetic field data, geological-structural mapping, paleotectonic, numerical modeling, paleogeographical and palinspastic reconstructions. When interpreting the DSS profiles, the classic velocity models are supplemented with seismic images obtained by the original finite-difference reflection/refraction migration method. The monograph included scientific study carried out at the S.I. Subbotin Institute of Geophysics of the National Academy of Sciences of Ukraine with the involvement of seismic and related geophysical data obtained as a result of conducting and interpreting regional wide-angle seismic profiles (WARR): DOBRE’99, PANCAKE and RomUkrSeis. Geological interpretation of reflection seismic profiles of the Ukrainian sector of the Black Sea, paleogeographical and palinspastic reconstructions contributed to the study of the evolution of the entire Black Sea region. The geological evolution of the Ukrainian Carpathians is reconstructed on the basis of updated data on stratigraphy, tectonics, lithology and sedimentology and palinspastic reconstructions. The structure and development of the DDB sedimentary cover was revealed by seismogeological sections along numerous reflection (CDP) seismic profiles. The tectonics of the Precambrian Ukrainian Shield, including the Kryvyi Rih-Kremenchug and Golovanivsk suture zones, were studed by geomagnetic field analysis and detailed geological and structural mapping.