Innervation of pulmonary veins: Morphologic pattern and pathways of nerves in the human fetus

Vaitkevičius, Raimundas; Saburkina, Inga; Žaliūnas, Remigijus; Paužienė, Neringa; Vaitkevičienė, Inga; Schauerte, Patrick; Pauža, Dainius Haroldas

doi:10.1016/j.aanat.2007.09.002

Cited by 5 publications

(2 citation statements)

References 30 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In the adult human LA, the area around the pulmonary veins is densely innervated ( Figure 4D ): many ganglionated plexuses with both sympathetic and parasympathetic fibers are found in this area. The right pulmonary veins are mostly innervated by the dorsal right atrial subplexus and the middle dorsal subplexus, whereas the left superior pulmonary vein is innervated by the left dorsal subplexus and the left inferior pulmonary vein is innervated by the left and middle dorsal subplexus ( Vaitkevicius et al, 2008 , 2009 ; Wickramasinghe and Patel, 2013 ). Sympathetic and parasympathetic innervation density are both especially high in the superior aspects of the superior pulmonary veins and the inferior aspects of the inferior pulmonary veins.…”

Section: Anatomical Evidence Of Regional Differences In Cardiac Innervation Density: Sympathetic and Parasympatheticmentioning

confidence: 99%

Asymmetry and Heterogeneity: Part and Parcel in Cardiac Autonomic Innervation and Function

et al. 2021

View full text Add to dashboard Cite

The cardiac autonomic nervous system (cANS) regulates cardiac adaptation to different demands. The heart is an asymmetrical organ, and in the selection of adequate treatment of cardiac diseases it may be relevant to take into account that the cANS also has sidedness as well as regional differences in anatomical, functional, and molecular characteristics. The left and right ventricles respond differently to adrenergic stimulation. Isoforms of nitric oxide synthase, which plays an important role in parasympathetic function, are also distributed asymmetrically across the heart. Treatment of cardiac disease heavily relies on affecting left-sided heart targets which are thought to apply to the right ventricle as well. Functional studies of the right ventricle have often been neglected. In addition, many principles have only been investigated in animals and not in humans. Anatomical and functional heterogeneity of the cANS in human tissue or subjects is highly valuable for understanding left- and right-sided cardiac pathology and for identifying novel treatment targets and modalities. Within this perspective, we aim to provide an overview and synthesis of anatomical and functional heterogeneity of the cANS in tissue or subjects, focusing on the human heart.

show abstract

Section: Anatomical Evidence Of Regional Differences In Cardiac Innervation Density: Sympathetic and Parasympatheticmentioning

confidence: 99%

Asymmetry and Heterogeneity: Part and Parcel in Cardiac Autonomic Innervation and Function

et al. 2021

View full text Add to dashboard Cite

show abstract

“…There are at least 7 ganglionated plexi (GP) located in the canine epicardium including 4 atrial GP and 3 ventricular GP [1]. Several studies have demonstrated that most autonomic nerve fibers penetrated from the atrial GP to the pulmonary vein (PV) [2,3]. And the ventricular GP, has long been regarded only relative to the function of ventricle,eg.…”

Section: Introductionmentioning

confidence: 99%

Autonomic Innervation from the Aortic Root Ventricular Ganglionated Plexi to the Pulmonary Vein: A Novel Pathway

T¹

2015

J Cardiovasc Med Cardiol

View full text Add to dashboard Cite

show abstract

Fetal Pulmonary Venous Return: From Basic Research to the Clinical Value of Doppler Assessment

Portela Dias,

Guedes-Martins

2023

Pediatr Cardiol

View full text Add to dashboard Cite

The fetal pulmonary circulation represents less than 25% of the fetal cardiac output. In comparison with the pulmonary arteries, studies on pulmonary veins are few and limited, and many questions remain to be answered. The literature reports that pulmonary veins play an important role in regulating vascular flow, forming an active segment of the pulmonary circulation. The development of more sophisticated ultrasonography technology has allowed the investigation of the extraparenchymal pulmonary veins and their waveform. The recognition of the pulmonary vein anatomy in echocardiography is important for the diagnosis of anomalous pulmonary venous connections, with a significant impact on prognosis. On the other hand, the identification of the normal pulmonary vein waveform seems to be a reliable way to study left heart function, with potential applicability in fetal and maternal pathology. Thus, the goal of this narrative review was to provide a clinically oriented perspective of the available literature on this topic.

show abstract

Innervation of pulmonary veins: Morphologic pattern and pathways of nerves in the human fetus

Cited by 5 publications

References 30 publications

Asymmetry and Heterogeneity: Part and Parcel in Cardiac Autonomic Innervation and Function

Asymmetry and Heterogeneity: Part and Parcel in Cardiac Autonomic Innervation and Function

Autonomic Innervation from the Aortic Root Ventricular Ganglionated Plexi to the Pulmonary Vein: A Novel Pathway

Fetal Pulmonary Venous Return: From Basic Research to the Clinical Value of Doppler Assessment

Contact Info

Product

Resources

About