Innovations and Future Directions in Head and Neck Microsurgical Reconstruction

Suchyta, Marissa; Mardini, Samir

doi:10.1016/j.cps.2016.11.009

Cited by 30 publications

(18 citation statements)

References 69 publications

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“…Reconstruction for complex cases most times require a free flap and may at times also require patient-matched implants or patient-matched rigid fixation. ICD-10: C41.0 Malignant neoplasm of bones of skull and face, C41.1 Malignant neoplasm of mandible PubMed Search: ((3D Printing) AND (Malignant Neoplasm Skull)) OR ((Rapid Prototyping) AND (Malignant Neoplasm Skull)) OR ((3D Printing) AND (Malignant Neoplasm Mandible)) OR ((Rapid Prototyping) AND (Malignant Neoplasm Mandible)) OR ((virtual surgical planning) AND (Malignant Neoplasm Mandible)) OR ((patient matched implant) AND (Malignant Neoplasm Mandible)) Results: [ 36 , 55 , 72 , 73 , 82 , 88 , 107 , 111 , 114 , 161 , 202 – 205 , 246 – 300 ] Malignant Neoplasms (Soft Tissue) : Malignant neoplasms of the soft tissue within the craniomaxillofacial region include cancers of the oral cavity (e.g. tongue, floor of mouth maxillary and mandibular gingiva), oropharynx, hypopharynx, orbit, skull base and larynx.…”

Section: Appendixmentioning

confidence: 99%

Radiological Society of North America (RSNA) 3D printing Special Interest Group (SIG): guidelines for medical 3D printing and appropriateness for clinical scenarios

et al. 2018

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Medical three-dimensional (3D) printing has expanded dramatically over the past three decades with growth in both facility adoption and the variety of medical applications. Consideration for each step required to create accurate 3D printed models from medical imaging data impacts patient care and management. In this paper, a writing group representing the Radiological Society of North America Special Interest Group on 3D Printing (SIG) provides recommendations that have been vetted and voted on by the SIG active membership. This body of work includes appropriate clinical use of anatomic models 3D printed for diagnostic use in the care of patients with specific medical conditions. The recommendations provide guidance for approaches and tools in medical 3D printing, from image acquisition, segmentation of the desired anatomy intended for 3D printing, creation of a 3D-printable model, and post-processing of 3D printed anatomic models for patient care.

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Section: Appendixmentioning

confidence: 99%

Radiological Society of North America (RSNA) 3D printing Special Interest Group (SIG): guidelines for medical 3D printing and appropriateness for clinical scenarios

et al. 2018

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“…Multifaceted content is exemplified by sessions on clinically applied concepts including bone marrow transplantation for hematological malignancies; nerve reconstruction in neurosurgery; facial reanimation and composite allotransplant in plastic and microsurgery; hybrid core decompression and osteochondral grafts in orthopedics; platelet-rich plasma interventions in physical and sports medicine; cell therapies for neurodegenerative, cardiac, and kidney disease; prenatal fetoscopic regenerative interventions; and neorganogenic regeneration for aerodigestive pathologies. 22–25 The range of presented clinical trials underscores the ongoing assessment and validation stage of emerging therapies, i.e., mesenchymal stem cells in amyotrophic lateral sclerosis and multiple systems atrophy; mononuclear cell therapy for hypoplastic left heart syndrome; lineage-specified cardiopoietic stem cells for chronic heart failure; stem cells for bronchiolitis obliterans, renal artery stenosis, avascular necrosis of the hip, and osteoarthritis of the knee; stem cell-coated fistula plugs for Crohn’s disease; stromal cells for host versus graft disease; and stem cells for relapsed ovarian cancer. 1,26–30…”

Section: Preparing the Next-generation Physicianmentioning

confidence: 99%

Regenerative medicine curriculum for next-generation physicians

et al. 2019

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Regenerative sciences are poised to transform clinical practice. The quest for regenerative solutions has, however, exposed a major gap in current healthcare education. A call for evidence-based adoption has underscored the necessity to establish rigorous regenerative medicine educational programs early in training. Here, we present a patient-centric regenerative medicine curriculum embedded into medical school core learning. Launched as a dedicated portal of new knowledge, learner proficiency was instilled by means of a discovery–translation–application blueprint. Using the “from the patient to the patient” paradigm, student experience recognized unmet patient needs, evolving regenerative technologies, and ensuing patient management solutions. Targeted on the deployment of a regenerative model of care, complementary subject matter included ethics, regulatory affairs, quality control, supply chain, and biobusiness. Completion of learning objectives was monitored by online tests, group teaching, simulated clinical examinations along with longitudinal continuity across medical school training and residency. Success was documented by increased awareness and proficiency in domain-relevant content, as well as specialty identification through practice exposure, research engagement, clinical acumen, and education-driven practice advancement. Early incorporation into mainstream medical education offers a tool to train next-generation healthcare providers equipped to adopt and deliver validated regenerative medicine solutions.

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“…Those that can accurately mimic the elasticity and flexibility of tissue can provide more realistic models of disease, 30 aid in anatomical models for interventional and surgical simulation 31 and more adaptable prostheses. 32 It is also possible that 3D printing from micro-CT may be surpassed by other forms of high-resolution imaging, such as synchrotron or lab-based radiation phase contrast imaging, which may offer higher contrast to noise ratio and improved soft tissue microstructure detail. [33][34][35] So far, it has been used to create 3D anatomical models of small insects 36 but may have human applications.…”

Section: Future Directionsmentioning

confidence: 99%

3D printing from microfocus computed tomography (micro-CT) in human specimens: education and future implications

Shelmerdine

Simcock

Hutchinson

et al. 2018

BJR

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Microfocus CT (micro-CT) is an imaging method that provides three-dimensional digital data sets with comparable resolution to light microscopy. Although it has traditionally been used for non-destructive testing in engineering, aerospace industries and in preclinical animal studies, new applications are rapidly becoming available in the clinical setting including post-mortem fetal imaging and pathological specimen analysis. Printing three-dimensional models from imaging data sets for educational purposes is well established in the medical literature, but typically using low resolution (0.7 mm voxel size) data acquired from CT or MR examinations. With higher resolution imaging (voxel sizes below 1 micron, <0.001 mm) at micro-CT, smaller structures can be better characterised, and data sets post-processed to create accurate anatomical models for review and handling. In this review, we provide examples of how three-dimensional printing of micro-CT imaged specimens can provide insight into craniofacial surgical applications, developmental cardiac anatomy, placental imaging, archaeological remains and high-resolution bone imaging. We conclude with other potential future usages of this emerging technique.

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Innovations and Future Directions in Head and Neck Microsurgical Reconstruction

Cited by 30 publications

References 69 publications

Radiological Society of North America (RSNA) 3D printing Special Interest Group (SIG): guidelines for medical 3D printing and appropriateness for clinical scenarios

Radiological Society of North America (RSNA) 3D printing Special Interest Group (SIG): guidelines for medical 3D printing and appropriateness for clinical scenarios

Regenerative medicine curriculum for next-generation physicians

3D printing from microfocus computed tomography (micro-CT) in human specimens: education and future implications

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