Innovations in Diagnostics and Treatment of Patients With Hypertriglyceridemia

Симерзин, В В; Фатенков, О В; Гаглоева, И В; Галкина, М А; Panisheva, YaA A; Панишева, Я А; Krasovskaya, MA A; Красовская, М А

doi:10.35693/2500-1388-2017-0-1-43-51

Cited by 2 publications

(1 citation statement)

References 23 publications

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“…Указанная проблема часто встречается у амбулаторных пациентов, когда они, находясь в состоянии субоптимального статуса (SHS) [2] и считая себя здоровыми, не обращаются к врачу. Ранняя диагностика и коррекция изменений микрофлоры кишечника может стать дополнительным инструментом улучшения качества жизни пациентов в амбулаторной практике [3]. Доказано, что коррекция микрофлоры применением пробиотических препаратов (содержащих бифидо-и лактобактерии) недостаточна эффективна [4,5]; выживаемость пробиотических микроорганизмов в желудочно-кишечном тракте животных не выше 0,0001%, а лактобактерий в желудочно-кишечном тракте человека -0,000000008% [6].…”

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Meta-prebiotics: a new way to control the intestinal microbiota

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Lyamin

et al. 2021

Science and Innovations in Medicine

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Objectives to analyze the quality and quantity of the intestinal microflora of relatively healthy people and/or of those who did not visit a doctor in the last 3 months, before and 1 month after taking a meta-prebiotic complex containing dietary fiber (inulin) and oligosaccharides (oligofructose). Material and methods. We examined the individuals who considered themselves healthy and/or did not consult a doctor during the past 3 months. To detect the presence of dyspeptic complaints, the clinical data were collected. 114 people with different suboptimal status and non-specific dyspeptic complaints were chosen for the study and underwent the clinical examination for the degree of gut microbiota imbalance before taking the meta-prebiotic complex. 78 people followed the course of the meta-prebiotic and were examined after 1 month after the start. Results. We have obtained new data on intestinal biocenosis at various suboptimal status in relatively healthy people: the total number of bacteria is insufficient. When using a meta-prebiotic complex containing inulin and oligofructose, the composition of the intestinal microflora was improved due to the decreased cases of detection of opportunistic enterobacteria and other gram-negative microorganisms. Conclusion. The significance of studying the intestinal microbiotic complex in patients with the increased suboptimal health status is proved, and the earlier active screening of this category of patients is recommended.

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