Purpose. Determination of the scientific foundations and practical principles of improving the system of innovative provision and transfer of science-intensive products of the Institute of Feed Research and Agriculture of Podillia of NAAS to the agro-industrial production of Podillia. Methods. Dialectic, general scientific methods of knowledge and analysis, basic provisions of economic science, monographic – to determine the theoretical foundations of the problem, the method of theoretical generalization – to carry out a critical analysis of the literature sources regarding the investigated problem; systematic approach and techniques of the abstract-logical method – to determine the practical foundations of the investigated problem. Results. The theoretical foundations have been summarized and the practical principles of improving the system of innovative provisioning and transfer of knowledge-intensive products of the Institute of Feed Research and Agriculture of Podillia of NAAS to the agricultural sector of the economy, in particular, Podillia region, have been determined. The essence of the category “system of innovative provision and transfer of innovations” (SiPiTi) has been determined. The main areas of improvement of the SiPiTi system have been identified: improving the provision of all types (stages) of innovative activity, adjusting the directions of innovative development of the institution, creating a portfolio of new science-intensive developments, improving the stimulation of the intellectual work of scientists, strengthening the competitiveness of innovations as a market product, concentrating own resources for the commercialization of existing innovations and creating new ones, strengthening the protection of intellectual property rights, holding regular online and offline exhibitions and fairs, improving consulting activities, etc. Conclusions. Improving the system of innovative provision and transfer of knowledge-intensive products will contribute to increasing the level of innovative potential of the institution, transferring innovations to the agricultural sector of the economy of the region and the country, raising the national innovation system for the development of agricultural sector and the entire country’s economy.