2021
DOI: 10.1002/mp.14677
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Innovative monochromatic x‐ray source for high‐quality and low‐dose medical imaging

Abstract: Purpose An estimated 377 million diagnostic and interventional radiological exams are performed annually in the United States and approximately 4 to 5 billion globally. All use x‐ray tubes that emit x‐rays over a broad energy band, a technology that is more than a century old. Only a small fraction of the radiation is useful for imaging while the remaining fraction either increases the radiation dose received by the patient or degrades the image. Monochromatic x‐rays can provide lower dose images in many of th… Show more

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Cited by 13 publications
(10 citation statements)
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“…Just as an example, the image quality of a 4.5 cm thick phantom with a 50% glandular-50% adipose equivalent tissue composition was evaluated by a standard, commercial, broadband mammography, and the monochromatic system. For equal SNR of the high contrast 100% glandular step wedge measured within a 5 mm × 5 mm region, the dose of the monochromatic image (0.18 mGy) was 7 times lower than that of the conventional image (1.26 mGy) [8]. Overall, the prototype system reduced radiation dose by factors of 5 to 10 times for the same SNRs as obtained from a conventional system.…”
Section: Most Recent Developments With Futuristic Potentialmentioning
confidence: 76%
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“…Just as an example, the image quality of a 4.5 cm thick phantom with a 50% glandular-50% adipose equivalent tissue composition was evaluated by a standard, commercial, broadband mammography, and the monochromatic system. For equal SNR of the high contrast 100% glandular step wedge measured within a 5 mm × 5 mm region, the dose of the monochromatic image (0.18 mGy) was 7 times lower than that of the conventional image (1.26 mGy) [8]. Overall, the prototype system reduced radiation dose by factors of 5 to 10 times for the same SNRs as obtained from a conventional system.…”
Section: Most Recent Developments With Futuristic Potentialmentioning
confidence: 76%
“…A most recent development in a monochromatic source fortunately meets all of the above 9 points in the wish list [8]. This innovative technology has garnered many patents as referenced in the paper.…”
Section: Most Recent Developments With Futuristic Potentialmentioning
confidence: 94%
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“…[30][31][32] Other approaches, such as a novel monochromatic source by Silver et al and ultra-compact X-ray-electron lasers, show future promise for imaging applications. 18,33 While the challenges above are nontrivial, we believe that the potential for Compton imaging as an efficient tomographic scheme renders the exploration worthwhile. Furthermore, it will be interesting to see how research in related fields, such as photon-counting detection, can help mature CST in the future.…”
Section: Discussionmentioning
confidence: 99%