Innovative nano-carriers in anticancer drug delivery-a comprehensive review

Dong, Pengcheng; Rakesh, K.P.; Manukumar, H.M.; Mohammed, Yasser Hussein Eissa; Karthik, C.S.; Sumathi, S.; Mallu, P.; Qin, Hua‐Li

doi:10.1016/j.bioorg.2019.01.019

Cited by 138 publications

(71 citation statements)

References 171 publications

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“…For instance, MNPs have been a great aid in medical diagnosis and treatment of diseases. 2 Among other cutting-edge medical applications, MNPs are integral components of drug carriers for magnetic drug delivery, 3,4 heat mediators in cancer therapy by magnetic fluid hyperthermia (MFH), 5 or contrast agents for magnetic resonance imaging (MRI). 6 MNPs are also highly relevant in matter of sensors and biosensors aimed to diverse analytes, 7 e.g., food contaminants, 8,9 environmental pollutants, 10 antibodies, 11 etc.…”

Section: Introductionmentioning

confidence: 99%

Expanding the tunability and applicability of exchange-coupled/decoupled magnetic nanocomposites

Granados-Miralles

Quesada

Saura-Múzquiz

et al. 2020

Mater. Chem. Front.

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Section: Introductionmentioning

confidence: 99%

Expanding the tunability and applicability of exchange-coupled/decoupled magnetic nanocomposites

Granados-Miralles

Quesada

Saura-Múzquiz

et al. 2020

Mater. Chem. Front.

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“…In the literature, the targeted drug delivery strategies are commonly divided into two types: passive targeting and active targeting [16,17]. Passive targeting exploits the so-called enhanced permeability and retention effect, and so its efficacy it is based on the accumulation of the nanoparticles in specific tissues: it is clear how the success of this technique is based on the circulation time.…”

Section: Targeted Drug Delivery: Selectivity Of the Delivery Process mentioning

confidence: 99%

“…Proteins are another class of molecules that can be used in order to realize nanoparticle coatings [17]. There are several types of these compounds in nature, and some of them are very interesting in targeted drug delivery.…”

Section: Proteins and Antibodies: A Very Promising Possibilitymentioning

confidence: 99%

“…Generally, this type of coating is realized with a methodology similar to the one previously explained. The great advantage of this molecule is the possibility of overcoming the opsonization problems typical of drug delivery systems due to its physiological peculiarity in blood circulation [17,100]. Figure 4 presents an example of the synthesis of a specific type of protein-coated nanoparticle.…”

Section: Proteins and Antibodies: A Very Promising Possibilitymentioning

confidence: 99%

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Coating and Functionalization Strategies for Nanogels and Nanoparticles for Selective Drug Delivery

Pinelli

Perale

Rossi

2020

Gels

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Drug delivery is a fascinating research field with several development opportunities. Great attention is now focused on colloidal systems, nanoparticles, and nanogels and on the possibility of modifying them in order to obtain precise targeted drug delivery systems. The aim of this review is to give an overview of the main available surface functionalization and coating strategies that can be adopted in order to modify the selectivity of the nanoparticles in the delivery process and obtain a final system with great targeted drug delivery ability. We also highlight the most important fields of application of these kinds of delivery systems and we propose a comparison between the advantages and disadvantages of the described functionalization strategies.

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“…Covalent and non-covalent hybridizations of nanostructures have been done by other bioorganic, organic and inorganic counterparts to explore the effects on the properties of both hybridized sides [12][13][14][15]. One of the important roles of nanostructures is their expected applications in therapeutics, in which drug delivery purposes are among the most favorable ones [16][17][18][19][20]. To this aim, the properties of nanostructures should be carefully characterized prior to assigning them for the application in living systems [21].…”

Section: Introductionmentioning

confidence: 99%

Non-Covalent Interactions of N-(4-CarboxyPhenyl)Phthalimide with CNTs

Molaeian¹,

Davood²,

Mirzaei

2020

Adv. J. Chem. B

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Non-covalent interactions of N-(4-carboxyphenyl)phthalimide (CPP) with carbon nanotubes (CNTs) have been investigated to see the effects of interactions on the properties of CPP, which is a medicinal compound. Two models of (3,3) armchair and (6,0) zigzag CNTs have been considered in this work. All structures have been optimized by density functional theory (DFT) calculations to evaluate the corresponding properties. Moreover, quadrupole coupling constants (CQ) have been evaluated at the atomic scale for the optimized structures. The results yielded stabilized CPP@CNT hybrids by effects of hybridization on the properties of both of CPP and CNT counterparts. The CQ parameters also indicate that the carbon atoms are very much important to detect the type of CNT whereas other atoms showed almost the same effects at the same situations. As a result, the CPP could be very well hybridized with the CNT through non-covalent interacting system.

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Innovative nano-carriers in anticancer drug delivery-a comprehensive review

Cited by 138 publications

References 171 publications

Expanding the tunability and applicability of exchange-coupled/decoupled magnetic nanocomposites

Expanding the tunability and applicability of exchange-coupled/decoupled magnetic nanocomposites

Coating and Functionalization Strategies for Nanogels and Nanoparticles for Selective Drug Delivery

Non-Covalent Interactions of N-(4-CarboxyPhenyl)Phthalimide with CNTs

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