Innovative technology of natural raw materials processing and biologically active complexes with systemic effect development

Tokhiriyon, Boisjoni; Poznyakovsky, V. M.; Vyalyh, Elena; Andrievskikh, Svetlana

doi:10.2991/ispc-19.2019.102

Cited by 7 publications

(4 citation statements)

References 5 publications

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“…The manufacturing technology of the encapsulated food supplement was developed. It has the following stages: raw-material preparing; mixture for encapsulation preparing; raw-material sieving and blending; encapsulating and sorting capsules by their appearance; and packing, packaging and labeling [ 12 , 13 , 14 , 15 , 19 , 20 , 21 , 22 , 23 , 24 ].…”

Section: Methodsmentioning

confidence: 99%

“…In addition to pharmaceutical-drug development, it has become necessary to create new anti-atherosclerotic medicines of natural origin, including biologically active food supplements with a multicomponent composition, which can act at various stages of the disease pathogenesis. This approach will promote diet therapy as part of combination therapy and improve preventive measures for people who do not show a clinical manifestation of the disease [ 9 , 10 , 11 , 12 , 13 , 14 , 15 ].…”

Section: Introductionmentioning

confidence: 99%

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Efficacy of Biologically Active Food Supplements for People with Atherosclerotic Vascular Changes

et al. 2022

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The current paper deals with the development of a new biologically active food supplement (BAFS) aimed at treating atherosclerosis. Since atherosclerosis is considered to be a disease of aging, the composition of the supplement includes such essential minerals as magnesium and potassium, which are commonly used to prevent atherosclerosis, as well as vitamins C, E and the B-group vitamins in order to address the needs of the elderly. The authors outline the supplement-manufacturing technology and discuss the clinical trial undertaken by patients, aged about 60 years, with peripheral atherosclerosis. The research methodology focuses on studying the effectiveness of the developed supplement by assessing the influence of the active ingredients on treating metabolic disorders. To establish the efficacy of the supplement, blood tests, ultrasound and physical examinations were applied. The combination therapy resulted in improved metabolism and an overall better performance of the cardiovascular system; therefore, the BASF can be recommended as part of combination therapy to prevent and treat atherosclerotic and age-related changes in blood vessels.

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Section: Methodsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Efficacy of Biologically Active Food Supplements for People with Atherosclerotic Vascular Changes

et al. 2022

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“…The influence of an increased intake of macro-and micro-nutrients when training was studied [1,2] and international practices were compared [3]. Foods of plant, animal, or mineral origin with documented beneficial effects have been used to boost metabolism and body functions, and prevent and treat infectious and non-infectious diseases [4][5][6][7][8][9][10][11][12]. Existing research conducted by Russian scientists demonstrated that antler products, including pantohematogen, can be successfully added to the diets of professional athletes to respond to their nutritional needs during training, competition, and recovery periods [13,14].…”

Section: Introductionmentioning

confidence: 99%

Ergogenic Dietary Supplements for Optimised Sports Performance

Latkov¹,

Tohiriyon²,

Pozdniakovskii³

et al. 2022

Pharmacophore

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The present study discusses the chemical composition, safety, and efficacy of a dietary supplement with pantohematogen, which is made from the blood of the Altai wapiti. The research methodology focuses on studying the effectiveness of the supplement by assessing the influence of its active ingredients on sports performance. The clinical study targeted professional rowers and mountaineers, whose high-intensity and prolonged training require carefully designed nutrition plans. Pantohematogen demonstrated its effectiveness resulting in improved blood biochemical composition, increased speed, and enhanced performance of rowers; while the positive impact made on mountaineers included better adaptation to high altitude, improved working memory, and better mental and physical capacity. To check compliance with the anti-doping regulations, anti-doping tests were taken and the results were negative. The findings indicate that dietary supplements with pantohematogen can successfully assist in maintaining the proper functioning of the nervous, immune, and cardiovascular systems when included in the nutrition plans of professional athletes.

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“…When the amount of food consumed is increased, the calorie content of the diet grows, which, in turn, leads to overweight and obesity and causes different diseases of civilization like cardiovascular and oncological diseases, etc. [2,[5][6][7][8][9][10][11][12][13][14][15][16][17].…”

Section: Introductionmentioning

confidence: 99%

Nutritional supplement for indigenous intestinal microflora: manufacturing, quality and effectiveness evaluation

et al. 2021

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The pharmaceutical composition of a nutritional supplement, which has a profound effect on the maintenance and development of the indigenous intestinal microflora, has been scientifically proven. The nutritional supplement is obtained by combining the encapsulation technology with the pellet technology to ensure that the pharmaceutical composition remains intact and the product appeals to consumers. The combination of encapsulation and pellet technology is highly beneficial to the manufacturing process as the delivery of the ingredients, which are very different in absorption and penetration rates, is improved, controlled and becomes very site-specific, while at the same time offering even distribution. The quality of the nutritional supplement has been proven and the product complies with the compulsory sanitary-hygienic and sanitarytoxicological regulations for dietary supplements. Clinical trials for the new nutritional supplement were performed to ensure the safety and the effectiveness of the product. Sixty volunteers aged from 33 to 72 were involved in the clinical trials. All of the volunteers were diagnosed with different intestinal microbiota disorders, among them a decreased number of microbial symbionts (bifidobacteria, lactobacilli, Escherichia coli (Lac +), the presence of Klebsiella pnenmoniae and opportunistic pathogens like Candida alticans. Patients with intestinal microbiota disorders were prescribed to take 1 capsule of the nutritional supplement twice a day for a period of 30 days together with other medicine prescribed to improve the biocenosis. Having taken part in the clinical trials, nearly 90% of patients, who had previously experienced such symptoms as bloating, gas, different abdominal pains, cramping, diarrhoea and constipation, demonstrated microbiota restoration, along with the overall health improvement. Considering the findings of the clinical trials, it should be noted that the use of ‘Panbiom’ nutritional supplement can play an important role in keeping the immune system healthy, with short chain fatty acids becoming the main focus of attention. Short chain fatty acids are the key to stimulating the immune response, as they support the regulatory T cells, prevent pathological changes and lessen the symptoms. The nutritional supplement composition and the manufacturing process were developed and tested at the scientific research-to-production facilities of Art-Life Scientific Production Association in Tomsk. All the mandatory documentation was obtained and fully complies with the requirements for nutritional supplements.

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Innovative technology of natural raw materials processing and biologically active complexes with systemic effect development

Cited by 7 publications

References 5 publications

Efficacy of Biologically Active Food Supplements for People with Atherosclerotic Vascular Changes

Efficacy of Biologically Active Food Supplements for People with Atherosclerotic Vascular Changes

Ergogenic Dietary Supplements for Optimised Sports Performance

Nutritional supplement for indigenous intestinal microflora: manufacturing, quality and effectiveness evaluation

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