Innovative thin silicon detectors for monitoring of therapeutic proton beams: preliminary beam tests

Vignati, A.; Monaco, V.; Attili, A.; Cartiglia, N.; Donetti, M.; Mazinani, M Fadavi; Fausti, F.; Giordanengo, S.; Ali, O. Hammad; Mandurrino, M.; Manganaro, L.; Ferrero, M.; Mazza, G.; Sacchi, R.; Sola, V.; Staiano, A.; Cirio, R.

doi:10.1088/1748-0221/12/12/c12056

Cited by 26 publications

(19 citation statements)

References 6 publications

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“…A new generation of silicon detectors based on UFSD technology and able to count single particles of therapeutic beams, and to measure the beam energy with time‐of‐flight techniques is under development by the medical physics group of the Turin division of the National Institute of Nuclear Physics (INFN) …”

Section: Detectors For Beam Monitoringmentioning

confidence: 99%

Dose detectors, sensors, and their applications

Giordanengo

2018

Medical Physics

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This article is intended to present the different types of particle and radiation detectors available for applications in particle therapy. Several types of detectors and sensors exist for measurements of absorbed dose in reference and nonreference conditions and the ones in use for beam monitoring. Therefore, this manuscript focuses on the following applications: (a) primary methods for dosimetry in ion beams, (b) measurements of absorbed dose in realistic patient‐specific scenarios with different dose delivery configurations, and (c) beam monitoring. Water and graphite calorimeters, Faraday cups, ionization based gas detectors are described first, followed by the description of the protocols for proton and ion dosimetry. Then films, scintillator and solid‐state detectors are reviewed. Finally, several types of ionization chambers (large, pinpoint, arrays of chambers arranged in regular 1D or 2D pattern, parallel‐plate configuration with large integral electrodes or with anode segmented in strips or pixels, multi‐wire, and the multi‐gap prototype) have been considered. New beam monitors to deal with a wide range of intensity and pulsed beams expected from new accelerators, different dose fractionation and advanced delivery techniques are presented. The existing detectors available for particle therapy have been described taking into account the different requirements for devices used in reference and nonreference conditions and the ones designed for beam monitoring.

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Section: Detectors For Beam Monitoringmentioning

confidence: 99%

Dose detectors, sensors, and their applications

Giordanengo

2018

Medical Physics

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“…For bunch detection, secondary particle detectors can be used [20,41], whereas scintillator-based hodoscopes are generally proposed for single particle counting, with timing resolutions of several hundred picoseconds [39,42]. Thin ultra-fast silicon detectors (UFSD) have been explored for such purpose [43]. Using another technology, we have shown that a temporal resolution close to 100 ps rms is expected by means of diamond detectors, on condition that large areas are available with detector-grade crystals [24,44].…”

Section: Need For a Beam Tagging Systemmentioning

confidence: 99%

On the Role of Single Particle Irradiation and Fast Timing for Efficient Online-Control in Particle Therapy

et al. 2020

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Within the frame of the CLaRyS collaboration, we discuss the assets of using a reduced-intensity in vivo treatment control phase during one or a few beam spots at the beginning of a particle therapy session. By doing so we can improve considerably the conditions for secondary radiation detection and particle radiography. This also makes Time-of-Flight (ToF) resolutions of 100 ps rms feasible for both the transmitted particles and secondary radiations, by means of a single-projectile counting mode using a beam-tagging monitor with time and position registration. This opens up new perspectives for prompt-gamma timing and Compton imaging for range verification. ToF-based proton computed tomography (CT) and ToF-assisted secondary proton vertex imaging in carbon therapy are also discussed, although for the latter, no evidence of any benefit at small observation angles is anticipated. The reduction of the beam intensity during one or a few spots on the various accelerators for particle therapy should not significantly reduce the patient workflow.

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“…LGAD is a recent technology in silicon systems featuring detection of particles in a wide energy range with improved accuracy for timing and tracking measurements [20]. The LGAD application in particle therapy has been also recently investigated [21]. In the proposed setup, the TEPC will provide the energy deposition ϵ directly in a tissue-equivalent medium while the LGADs will offer information about particle spatial distribution with a precision of about 200 or 300 μm, depending on the chosen configuration.…”

Section: Introductionmentioning

confidence: 99%

A Novel Hybrid Microdosimeter for Radiation Field Characterization Based on the Tissue Equivalent Proportional Counter Detector and Low Gain Avalanche Detectors Tracker: A Feasibility Study

et al. 2021

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In microdosimetry, lineal energies y are calculated from energy depositions ϵ inside the microdosimeter divided by the mean chord length, whose value is based on geometrical assumptions on both the detector and the radiation field. This work presents an innovative two-stages hybrid detector (HDM: hybrid detector for microdosimetry) composed by a tissue equivalent proportional counter and a silicon tracker made of 4 low gain avalanche diode. This design provides a direct measurement of energy deposition in tissue as well as particles tracking with a submillimeter lateral spatial resolution. The data collected by the detector allow to obtain the real track length traversed by each particle in the tissue equivalent proportional counter and thus estimates microdosimetry spectra without the mean chord length approximation. Using Geant4 toolkit, we investigated HDM performances in terms of detection and tracking efficiencies when placed in water and exposed to protons and carbon ions in the therapeutic energy range. The results indicate that the mean chord length approximation underestimate particles with short track, which often are characterized by a high energy deposition and thus can be biologically relevant. Tracking efficiency depends on the low gain avalanche diode configurations: 34 strips sensors have a higher detection efficiency but lower spatial resolution than 71 strips sensors. Further studies will be performed both with Geant4 and experimentally to optimize the detector design on the bases of the radiation field of interest.The main purpose of HDM is to improve the assessment of the radiation biological effectiveness via microdosimetric measurements, exploiting a new definition of the lineal energy (yT), defined as the energy deposition ϵ inside the microdosimeter divided by the real track length of the particle.

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Innovative thin silicon detectors for monitoring of therapeutic proton beams: preliminary beam tests

Cited by 26 publications

References 6 publications

Dose detectors, sensors, and their applications

Dose detectors, sensors, and their applications

On the Role of Single Particle Irradiation and Fast Timing for Efficient Online-Control in Particle Therapy

A Novel Hybrid Microdosimeter for Radiation Field Characterization Based on the Tissue Equivalent Proportional Counter Detector and Low Gain Avalanche Detectors Tracker: A Feasibility Study

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