Inorganic fullerene-like molybdenum selenide with good biocompatibility synthesized by laser ablation in liquids

Abstract

The fabrication of inorganic fullerene-like nanoparticles (IFNPs) is an attractive idea due to their unique structures and various potential applications. To date, IFNPs have been made from numerous compounds with layered two-dimensional structures, based on various synthetic methods. Here we have demonstrated for the first time that inorganic fullerene-like molybdenum selenide nanoparticles (MoSe IFNPs) can be synthesized by laser ablating a molybdenum selenide target in 30 vol % ethanol/water mixture at ambient temperature and pressure. The formation mechanism was proposed to elucidate the production of MoSe IFNPs in the process of laser ablation in liquids (LAL). The appropriate solvent facilitates the condensation of the plasma plume created by LAL to planar MoSe. Then, laser-induced high temperature and high pressure lead to the formation of a vacancy in the planar MoSe, causing the generation of nucleation and growth of the MoSe IFNPs. In addition, a CCK-8 (cell counting kit-8) assay and a cell viability assay were performed to examine the cytotoxic behavior and the effect on cell viability of MoSe IFNPs. The results show that MoSe IFNPs are reasonably nontoxic and biocompatible with the given cells, showing they have significant potential in biomedical applications.

Nanocomposite of Poly(l-Lactic Acid) with Inorganic Nanotubes of WS2

“…Obviously, the nucleation of PLLA crystallites during the solvent evaporation was a prime factor in enhancing the mechanical properties of the polymer matrix. This study, together with the fact that these nanotubes are found to exhibit minor toxicity [34][35][36][37][38], opens up several opportunities to further explore these nanocomposites for different applications.…”

“…Furthermore, the addition of the nanotubes to different gels [32,33] and polymer matrices [34] in small amounts leads to a precipitous reduction in the friction forces, which may have important ramifications on numerous medical and other technologies. Equally important is the fact that several studies have indicated that IF/INT of WS 2 (MoS 2 ) are non-toxic and biocompatible [34][35][36][37][38]. One of the challenges in nanocomposites is the compatibility between the polymer matrix and the nanofillers, which entails that the interfacial interaction between the surfaces of the two phases cannot be easily tuned and matched.…”

An overview of the recent advances in inorganic nanotubes

“…Moreover, due to their being good lubricants, the addition of IF/INT to polymer blends does not lead to large increase in the viscosity, or sometime incur reduced viscosity, which has substantial implications for the processing and production costs of the polymer nanocomposites in industrial environment. Nanoparticles of MX 2 materials, including IF/INT were found to be relatively nontoxic and benign up to high concentrations (>0.1 mg/ml), [181][182][183] offering them potential applications in different medical technologies. Another important area of research is in shock absorbance, which is relevant to many applications including the automotive industry, sport, prostheses, self-protecting jackets and many more.…”

Unveiling the Structure of MoSx Nanocrystals Produced upon Laser Fragmentation of MoS2 Platelets

“…Besides this, zero-dimensional (0D) TMDs have been found to exhibit high stability and extraordinary optoelectronic properties due to quantum confinement effects. − Such low-dimensional materials found numerous applications in electrochemical photocatalysis, , bioimaging, , and optoelectronic devices . MoS 2 nanostructures, in particular, have been synthesized with different methods, such as ionic liquid-assisted grinding exfoliation, hydrothermal routes, electrochemical exfoliation, colloidal methods at high temperature, laser ablation in liquids, − and via an induced Fenton reaction . Among them, the grinding exfoliation and the hydrothermal methods are time-consuming, considering that the first requires multiple centrifugation steps for the size selection of the particles whereas the second demands 18 h of reaction at 220 °C.…”