Inorganic Nanoarchitectonics for Biological Applications

Ariga, Katsuhiko; Ji, Qingmin; McShane, Michael J.; Lvov, Yuri; Vinu, Ajayan; Hill, Jonathan P.

doi:10.1021/cm202281m

Cited by 206 publications

(107 citation statements)

References 218 publications

Supporting

Mentioning

107

Contrasting

Order By: Relevance

“…As a method of assembling functional thin film nanomaterials, the layer-by-layer (LbL) technique offers many attractive features. 63 LbL assembly involves the consecutive adsorption of oppositely charged macromolecules onto a substrate, and its benefits include facile fabrication, and the possibility to coat a variety of geometries, to embed bioactive species into films, and to control morphology/composition through numerous control variables such as polymer type, solution salt, and pH. 64,65 Several studies have addressed the LbL assembly of carbon nanotubes.…”

Section: Discussionmentioning

confidence: 99%

Carbon nanotube bundling: influence on layer-by-layer assembly and antimicrobial activity

et al. 2013

View full text Add to dashboard Cite

Antimicrobial surfaces are potentially useful for a variety of health care related applications. Single walled carbon nanotubes (SWNT) have shown promise as antimicrobial agents, but important questions persist concerning the effects of tube bundling, a common phenomenon owing to strong hydrophobicity. We investigate 15 here the influence of bundling on the layer-by-layer (LbL) assembly of SWNT with charged polymers, and on the antimicrobial properties of the resultant films. We employ a poly(ethylene glycol) functionalized phospholipid (PL-PEG) to disperse SWNT in aqueous solution, and consider cases where SWNT are dispersed i) as essentially isolated objects and ii) as small bundles. Quartz crystal microgravimetry 20 with dissipation (QCMD) and ellipsometry measurements show the bundled SWNT system to adsorb in an unusually strong fashion -with layers twice (when hydrated) and three times (when dried) as thick as those of isolated SWNT. Molecular dynamics simulation reveals a lower PL-PEG density and degree of solution extension on bundled versus isolated SWNT. These, and especially the lower polymer density 25 results in a lower degree of steric repulsion, which together with stronger van der Waals attraction, may explain the thicker adsorbed layers. Scanning electron micrographs reveal Escherichia coli on films with bundled SWNT to be essentially engulfed by the nanotubes, whereas the bacteria rest upon films with isolated SWNT. While both systems inactivate 90% of bacteria in 24 h, the bundled SWNT system is 30 "fast-acting," reaching this inactivation rate in 1 h. This study demonstrates the significant impact of SWNT bundling on LbL assembly, explores its microscopic origins, and illustrates its use toward bacteria-engulfing, fast-acting, antimicrobial coatings. IntroductionThe impressive physical, mechanical, chemical, electronic, and optical properties of carbon nanotubes (CNT) have established them as a primary research focus since their discovery by Iijima. 1 Research has focussed on developing applications in energy production and storage systems, 2 reinforcements for highperformance composites, 3 sensing materials, 4, 5 drug delivery vehicles, 6, 7 cancer therapeutics, 8,9 and antimicrobial agents. 10,11 Although discovered only recently, the antimicrobial activity of CNT has attracted significant attention. [11][12][13][14][15][16][17] Antimicrobial materials are designed to kill bacteria, and could be used to prevent the infection of medical devices. There are approximately 2 million cases of nosocomial infections in the US annually, and half are associated with implantable devices.18 Thus far, the focus has been primarily on bio-inspired antimicrobial surfaces such as antimicrobial peptides, bacteriolytic enzymes and essential oils, antimicrobial polymers with protonated amine groups, and various antibiotics. [19][20][21] CNT possess certain advantages over other antimicrobial agents: they are highly stable, do not leach over time, are easy to functionalize, and are proving to be compatible with ...

show abstract

Section: Discussionmentioning

confidence: 99%

Carbon nanotube bundling: influence on layer-by-layer assembly and antimicrobial activity

et al. 2013

View full text Add to dashboard Cite

show abstract

“…1,2 However, because organic and inorganic autofluorophores are omnipresent in nature, very often the background signal from fluorochromes other than targeted probes or the autofluorescence under UV-visible excitation have to be eliminated. 1 This discrimination could be available using (i) NIR excitation source (ii) a time-resolved fluorescence microscopy (TRFM) technique operating in the frequency domain or (iii) a time-gated luminescence microscopy (TGLM) technique operating in the time domain.…”

Section: -Introductionmentioning

confidence: 99%

Time-gated luminescence bioimaging with new luminescent nanocolloids based on [Mo₆I₈(C₂F₅COO)₆]²⁻metal atom clusters

Neaime

Amela-Cortés

Grasset

et al. 2016

Phys. Chem. Chem. Phys.

View full text Add to dashboard Cite

show abstract

“…The preparation of thin films by the Langmuir-Blodgett technique from exfoliated platelets of clays has also been reported [120][121][122]. Inorganic-organic multilayered films have also been prepared via alternate adsorption of a cationic species and an anionic sheet of an exfoliated layered solid (Layer-by-Layer deposition technique, hereafter abbreviated as LbL technique) [123][124][125][126][127][128][129][130]. In order to apply LbL for the fabrication of thin films, swelling of layered solids into nano dimension is a basic prerequisite.…”

Section: Forms Of Intercalation Compoundsmentioning

confidence: 99%

Photochromic Intercalation Compounds

Okada

Sohmiya

Ogawa

2015

Photofunctional Layered Materials

View full text Add to dashboard Cite

Inorganic Nanoarchitectonics for Biological Applications

Abstract: JI, Q.; MCSHANE, M. J.; LVOV, Y. M.; VINU, A.; HILL, J. P.; Chem. Mater. 24 (2012) 5, 728-737, http://dx.

Cited by 206 publications

References 218 publications

Carbon nanotube bundling: influence on layer-by-layer assembly and antimicrobial activity

Carbon nanotube bundling: influence on layer-by-layer assembly and antimicrobial activity

Time-gated luminescence bioimaging with new luminescent nanocolloids based on [Mo₆I₈(C₂F₅COO)₆]²⁻metal atom clusters

Photochromic Intercalation Compounds

Contact Info

Product

Resources

About

Inorganic Nanoarchitectonics for Biological Applications

Abstract: JI, Q.; MCSHANE, M. J.; LVOV, Y. M.; VINU, A.; HILL, J. P.; Chem. Mater. 24 (2012) 5, 728-737, http://dx.

Cited by 206 publications

References 218 publications

Carbon nanotube bundling: influence on layer-by-layer assembly and antimicrobial activity

Carbon nanotube bundling: influence on layer-by-layer assembly and antimicrobial activity

Time-gated luminescence bioimaging with new luminescent nanocolloids based on [Mo6I8(C2F5COO)6]2−metal atom clusters

Photochromic Intercalation Compounds

Contact Info

Product

Resources

About

Time-gated luminescence bioimaging with new luminescent nanocolloids based on [Mo₆I₈(C₂F₅COO)₆]²⁻metal atom clusters